Orexo issues a SEK 500 million bond loan on the Swedish bond market

Uppsala, Sweden – April 30, 2014 - Orexo AB (publ) has decided to issue a four
-year senior unsecured bond loan of SEK 500 million with maturity on May 9,
2018. The bond loan will have a floating interest rate of Stibor 3m + 4.00% and
a total framework amount of SEK 1 billion. Orexo intends to apply for listing of
the bonds on NASDAQ OMX Stockholm.

Pareto Securities AB has acted as sole bookrunner and Gernandt & Danielsson has
acted as legal adviser to Pareto. Vinge has acted as legal adviser to Orexo.

“We are very pleased with the solid interest for the bond amongst investors. The
issue strengthens our financial position further and is an important step in
financing the continued expansion of Zubsolv, as well as to decrease current
bank debt”, said Nikolaj Sørensen, President and CEO of Orexo.

For additional information, please contact:
Henrik Juuel, CFO and EVP
Phone: +46 (0)72-220 94 77, E-mail: ir@orexo.com

Daniel Gabriel
Corporate Finance, Pareto Securities
Phone: +46 (0)8-402 51 95, E-mail: daniel.gabriel@paretosec.com

About Orexo
Orexo is a specialty pharma company with commercial operations in the United
States and R&D in Sweden developing improved treatments using proprietary drug
delivery technology and commercial operations in the United States. The company
is commercializing its proprietary product, Zubsolv®, for maintenance treatment
of opioid dependence, in the United States. Zubsolv is a novel formulation of
buprenorphine and naloxone using Orexo’s extensive knowledge in sublingual
technologies. Orexo has a portfolio of two approved and revenue generating
products currently marketed under license in the EU and US. Orexo AB, with its
headquarters in Sweden, is listed on NASDAQ OMX Stockholm Exchange and its
American Depositary Receipts (ADRs) trade on the OTCQX marketplace in the U.S.
under the symbol, “ORXOY”. The largest shareholders are Novo A/S and HealthCap.

For information about Orexo please visit www.orexo.com

This is information required to be disclosed by Orexo AB (publ) pursuant to the
Swedish Securities Markets Act and/or the Swedish Financial Instruments Trading
Act. This information was released for publication on April 30, 2014, at 1:15pm
CET.