ISFIYA, ISRAEL, June 02, 2018 (GLOBE NEWSWIRE) -- Check-Cap Ltd. (the “Company” or “Check-Cap”) (NASDAQ: CHEK, CHEKW, CHEKZ), a clinical stage medical diagnostics company engaged in the development of C-Scan®, an ingestible capsule preparation-free, colorectal cancer screening, today announced the oral presentation on the feasibility of prepless colorectal cancer (CRC) screening with the multi-center clinical study submitted for the CE Mark approval of C-Scan, received in January 2018, at Digestive Disease Week in Washington DC, taking place on June 2-5, 2018.
Dr. Elizabeth E. Half, MD, Head of GI Cancer Prevention Unit and Familial Cancer Syndrome Clinic Gastroenterology Institute at the RAMBAM Healthcare Campus presents a comparative study entitled "Prepless CRC Screening is Feasible with a Novel X-ray Imaging Capsule," at the ongoing Advances in Colorectal Polyp Detection Session 1410, Convention Center Room 207. Dr. Half’s presentation highlights that study data from 45 analyzed patients showed capsule and FIT sensitivity (ability to correctly identify polyps) of 44% and 37%, respectively, with capsule sensitivity increasing to 78% when >50% of the colon surface area was imaged and a linear correlation was observed between imaged area and sensitivity. In addition, capsule safety in the study was demonstrated, with no reported adverse events, low radiation (average radiation dose of 0.05ms), and transit time of 52±32 hrs. Further, in an updated scanning algorithm, retrospectively implemented on the study data and recently featured in a May 2018 article in Gut, a dramatic increase in number of subjects with imaged area >50% was shown, from 21/45 to 41/45 (from 46% to 91%), following the new algorithm implementation. Capsule specificity (ability to correctly identify lack of polyps) in those cases approached 90%.
Digestive Disease Week is one of the world's largest gathering of physicians, researchers and industry in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery, with over 14,000 in annual attendance.
About Check-Cap
Check-Cap is a clinical-stage medical diagnostics company developing C-Scan®, an ingestible capsule-based system for preparation-free colorectal cancer screening.
Utilizing innovative ultra-low dose X-ray and wireless communication technologies, the capsule generates information on the contours of the inside of the colon as it passes naturally. This information is used to create a 3D map of the colon, which allows physicians to look for polyps and other abnormalities. Designed to improve the patient experience and increase the willingness of individuals to participate in recommended colorectal cancer screening, C-Scan removes many frequently-cited barriers, such as laxative bowel preparation, invasiveness and sedation.
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