Prostate Cancer Pipeline Insights: Comprehensive Analysis of Key Emerging Therapies and Pharmaceutical Companies

With over 900 key pharmaceutical companies working, the Prostate cancer pipeline projects a robust and promising picture in near future, says DelveInsight


Los Angeles, USA, March 22, 2021 (GLOBE NEWSWIRE) -- Prostate Cancer Pipeline Insights: Comprehensive Analysis of Key Emerging Therapies and Pharmaceutical Companies  

With over 900 key pharmaceutical companies working, the Prostate cancer pipeline projects a robust and promising picture in near future, says DelveInsight 

DelveInsight’s Prostate Cancer Pipeline Insightsreport highlights major breakthroughs happening in the domain, emerging therapies in different stages of clinical development, segmented based on MoA, RoA, molecule types, drug delivery platform, and so on.

Some of the key highlights from the Prostate Cancer Drug Pipeline report: 

  • The present Prostate cancer treatment comprises surgery, radiation therapy, and proton beam therapy. Chemotherapy, hormonal therapy, cryosurgery, and high-intensity focused ultrasound (HIFU) are also among the prescribed treatment strategies. 
  • Out of all the emerging Prostate cancer drugs, SHR3860, Cabozantinib, Aglatimagene besadenovec, LY01005, [18F]PSMA-1007, HC-1119, VERU-111, and ARV 110 are expected to enter the market in the next decade. 
  • Key companies dedicated to advance the Prostate cancer drug pipeline are Pfizer, Myovant Biosciences, Effector Therapeutics, Mediolanum, Merck, ESSA Pharma, Sanofi, Astellas Pharma, AstraZeneca, Bayer, Janssen research & development LLC, Bristol Myers Squibb, Eli Lilly and Company, Amgen, POINT Biopharma, Hinnova Pharmaceuticals, Sophiris Bio, Ultimovacs, Foresee Pharmaceuticals, Luye Pharma Group, Abbott, AB science, Ferring pharmaceuticals, Jiangsu HengRui Medicine, Hoffmann-La Roche, Novartis, Celgene, Endocyte, Millennium Pharmaceuticals, Medivation, Veru, Progenics Pharmaceuticals, Boehringer Ingelheim, US Biotest, Antev, Elevation oncology, Abgenix, Astellas Pharma, Orion Pharma, Clovis Oncology, Exelixis, Takeda, Novus Therapeutics, Candel Therapeutics, Ipsen, MEI Pharma, Aragon Pharmaceuticals, MedImmune,  CytRx, Tmunity Therapeutics, Inovio Pharmaceuticals, Forma Therapeutics, Luye Pharma, Health Ever Bio-Tech, Advaxis, Corcept Therapeutics and several others.  
  • Novel Prostate cancer pipeline products include P PSMA 101, Autologous adipose-derived mesenchymal stem cell therapy, EPI 7386, ODM 208, MCS 8, ADXS PSA, Exicorilant, VERU-100.
  • Vaccitech is currently developing ChAdOx1-MVA 5T4 vaccine (VTP-008). This vaccine will be used in combination with the immunotherapy drug called nivolumab which is an anti-PD-1 (Programmed Death protein-1) monoclonal antibody. 
  • Ultimovacs has started the clinical evaluation of Novel TET Tetanus-Epitope Targeting (TET)-platform based TENDU Vaccine for the treatment of Prostate cancer.
  • In October 2020, Foresee Pharmaceuticals announced that 505(b)(2) New Drug Application (NDA) for FP-001 LMIS 50mg, or CAMCEVI 42MG, a ready-to-use 6-month depot formulation of leuprolide mesylate, has been accepted for review by the U.S. Food and Drug Administration (FDA).
  • Takeda has granted Myovant an exclusive, worldwide license (excluding Japan and certain other Asian countries). U.S Food and Drug Administration approved the first oral gonadotropin-releasing hormone (GnRH) receptor antagonist Relugolix on December 18, 2020, for the treatment of adult patients with advanced prostate cancer.

Request for Sample @ Prostate Cancer Therapeutic Assessment 

Prostate cancer originates from the prostate gland located in the pelvis, next to the bladder, of men. It is the second-leading cause of death due to cancers in men in the U.S. About 1 in 9 men are diagnosed with prostate cancer in their lifetime. Growths in the prostate can be benign (not cancer) or malignant (cancer).

Prostate Cancer Drug Profiles 

Tomivosertib: Effector Therapeutics
Tomivosertib (also known as eFT508) is a novel, potent and highly selective oral small molecule inhibitor of mitogen-activated protein kinase interacting kinases 1 and 2, or collectively, MNK1/2.  MNK1/2 plays a crucial role in the development of many tumors, including by controlling in a coordinated manner the expression of multiple factors that attenuate an immune response. 

Tomivosertib is currently in the Phase II stage of development. This Phase 2 study examines the efficacy, safety, tolerability, and pharmacokinetics (PK) of eFT508 (tomivosertib) in metastatic castration-resistant prostate cancer patients who have documented PSA progression on treatment with one of three hormone therapies – abiraterone, enzalutamide or apalutamide and for whom no curative therapy exists. The primary objective of this study is to assess the anti-tumor response to eFT508 (tomivosertib) in mCRPC. 

Gain more rich insights into drug profiles, trials, stages @ Prostate cancer drug pipeline 

Prostate Cancer Emerging Drugs Profile at a Glance

DrugCompanyClinical PhaseMoARoA
ARV-110ArvinasPhase I/IIAndrogen receptor degradation enhancersOral
LMIS 50 mgForesee PharmaceuticalsPreregistrationGonadotropin-releasing hormone stimulantsSubcutaneous
TomivosertibEffector TherapeuticsPhase IIMKNK1 protein inhibitors; MKNK2 protein inhibitorsOral
ExicorilantCorcept TherapeuticsPhase I/IIGlucocorticoid receptor antagonistsOral
VERU 111Veru HealthcarePhase I/IITubulin polymerisation inhibitorsOral
 ODM 208OrionPhase IICholesterol side-chain cleavage enzyme inhibitorsOral
EPI 7386ESSA PharmaPhase IAndrogen receptor antagonistsOral
LAE001NovartisPhase I/IISteroid 17-alpha-hydroxylase inhibitorsOral
CapivasertibAstraZenecaPhase IIIProto-oncogene protein c-akt inhibitorsOral

Prostate Cancer Therapeutic Assessment 

By Product Type

  • Mono
  • Combination

By Stage

  • Discovery 
  • Pre-clinical
  • Phase I
  • Phase II
  • Phase III
  • Pre-registration

By Route of Administration

  • Oral
  • Intravenous
  • Inhalation
  • Subcutaneous
  • Infusion
  • Intradermal
  • Intramuscular
  • Intranasal
  • Parenteral
  • Topical

By Molecule Type

  • Gene therapy
  • Small molecules
  • Stem cell therapy
  • Gene therapies
  • Vaccines
  • Polymers
  • Peptides
  • Monoclonal antibodies

By Mechanism of Action

  • Protease Inhibitors
  • Immunomodulatory 

By Targets

  • Protease
  • Immune system
  • Multiple kinases

By Stage and Molecule Type
By Stage and Route of Administration
By Stage and Product Type

Get a holistic view of the pipeline analysis @ Prostate Cancer Drug Pipeline and Emerging Trends 

Scope of the Report

Coverage: Global
Key Players: Pfizer, Myovant Biosciences, Effector Therapeutics, Mediolanum, Merck, ESSA Pharma, Sanofi, Astellas Pharma, AstraZeneca, Bayer, Janssen research & development LLC, Bristol Myers Squibb, Eli Lilly and Company, Amgen, POINT Biopharma, Hinnova Pharmaceuticals, Sophiris Bio, Ultimovacs, Foresee Pharmaceuticals, Luye Pharma Group, Abbott, AB science, Ferring pharmaceuticals, Jiangsu HengRui Medicine, Hoffmann-La Roche, Novartis, Celgene, Endocyte, Millennium Pharmaceuticals, Medivation, Veru, Progenics Pharmaceuticals, Boehringer Ingelheim, US Biotest, Antev, Elevation oncology, Abgenix, Astellas Pharma, Orion Pharma, Clovis Oncology, Exelixis, Takeda, Novus Therapeutics, Candel Therapeutics, Ipsen, MEI Pharma, Aragon Pharmaceuticals, MedImmune,  CytRx, Tmunity Therapeutics, Inovio Pharmaceuticals, Forma Therapeutics, Luye Pharma, Health Ever Bio-Tech, Advaxis, Corcept Therapeutics, and several others. 

Key Questions Answered 

  • How many companies are developing Prostate Cancer drugs?
  • How many Prostate Cancer drugs are developed by each company?
  • How many emerging drugs are in the mid-stage, and late-stage of development for the treatment of Prostate Cancer?
  • What are the key collaborations (Industry–Industry, Industry-Academia), Mergers and acquisitions, licensing activities related to Prostate Cancer therapeutics?
  • What are the recent trends, drug types, and novel technologies developed to overcome the limitation of existing therapies?
  • What are the clinical studies going on for Prostate Cancer and its status?
  • What are the key designations that have been granted to emerging drugs?

Got queries? Get answers @ Prostate Cancer Emerging Therapies 

Table of Contents 

1Introduction
2Executive Summary
3Prostate Cancer Overview
4Prostate cancer Pipeline Pipeline Therapeutics
5Prostate cancer Pipeline Therapeutic Assessment
6Prostate Cancer – DelveInsight’s Analytical Perspective
7In-depth Commercial Prostate cancer Pipeline Assessment
8Prostate Cancer Collaboration Deals
9Late Stage Prostate cancer Pipeline Products (Phase III and Preregistration)
10Mid-Stage Prostate cancer Pipeline Products (Phase II)
11Pre-clinical and Discovery Stage Prostate cancer Pipeline Products
12Inactive Prostate cancer Pipeline Products
13Prostate Cancer Key Companies
14Prostate Cancer Key Products
15Prostate Cancer Unmet Needs
16Prostate Cancer Market Drivers and Barriers
17Prostate Cancer Future Perspectives and Conclusion
18Prostate Cancer Analyst Views
20Appendix

Reach out for a live demo of the report @ Prostate Cancer Pipeline Insights

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