Active Pharmaceutical Ingredients Market Size to Hit USD 512.13 Billion by 2030 at 7.98% CAGR – Report by Market Research Future (MRFR)

Active Pharmaceutical Ingredients Market Trends And Insights By Manufacturing Process (Captive Manufacturing and Contract Manufacturing), By Type of Synthesis (Synthetic and Biotech), By API Formulation (Generic API and Branded/Innovative API), By Application (Cardiovascular Disease, Oncology, Neurological Disorders, Orthopedic Disorders, Respiratory, Gastrointestinal Disorders, Urology, and others), By Molecules (Large Molecule and Small Molecule), And By Region (North America, Europe, Asia-Pacific, And Rest Of The World), Competitive Market Growth, Size, Share and Forecast to 2030


New York, USA, May 04, 2023 (GLOBE NEWSWIRE) -- Active Pharmaceutical Ingredients (API) Market Overview

Market Research Future (MRFR) 's report highlights “Active Pharmaceutical Ingredients Market Information By Manufacturing Process, Type of Synthesis, API Formulation, Application, Molecules, And Region - Forecast till 2030", the market size was valued at USD 277.1 billion in 2021 and is projected to grow from USD 299.21 billion in 2022 to USD 512.13 billion by 2030, exhibiting a compound annual growth rate (CAGR) of 7.98% during the forecast period (2022 - 2030)

Market Scope

The term "active pharmaceutical ingredient" (API) refers to a drug's active ingredient. To put it simply, API is the component of a drug that causes the desired effects. Drugs are typically created from a variety of ingredients. The active ingredient is the API. An active drug element is the active pharmaceutical ingredient (API). Drugs comprise various ingredients, with the API serving as the main constituent. Excipients are additional ingredients typically identified and ought to be harmless to biological systems. The formulation is the process of composing and optimizing the combination of ingredients used in medicine. There are not many medications that can treat a variety of symptoms with multiple active APIs. Most of the API production has been handled by regional pharmaceutical firms.

Other components, often called excipients, must be physiologically harmless and comprise a significant portion of drug products. The formulation is composing and optimizing this concoction of pharmaceutical ingredients. Some medications treat various symptoms or function complexly by combining several active APIs. Local pharmaceutical firms have historically produced most APIs. The main steps in the API process are the multi-step drug synthesis and the process of fermentation, crystallization, grinding, labeling, drying, packing, purification, and testing. Some drugs that have undergone API treatment may be bulk-finished goods. Furthermore, due to safety concerns, regulatory agencies worldwide pay close attention to the active pharmaceutical components in pediatric formulations.

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Report Scope:

Report AttributeDetails
Market Size in 2030USD 512.13 Billion
CAGR7.98%
Base Year2021
Forecast Period2022-2030
Historical Data2020
Forecast UnitsValue (USD Billion)
Report CoverageRevenue Forecast, Competitive Landscape, Growth Factors, and Trends
Segments CoveredBy Manufacturing Process, Type of Synthesis, API Formulation, Application And Molecules
Geographies CoveredNorth America, Europe, Asia-Pacific, and Rest of the World (RoW)
Key Market DriversRaised incidences of chronic diseases and an upsurge in novel drug applications
Joint ventures and geographical expansions

Active Pharmaceutical Ingredients (API) Market Competitive Landscape:

The robust contenders in the active pharmaceutical ingredients market are:

  • Sanofi SA (France)
  • Merck & Co. Inc (US)
  • Boehringer Ingelheim GmbH (UK)
  • GlaxoSmithKline Plc (UK)
  • Novartis AG (UK)
  • Hoffmann-La Roche Ltd (Switzerland)
  • Pfizer Inc (US)
  • Abbott (US)
  • Bayer AG(UK)
  • Eli Lilly and Company (US)
  • Teva Pharmaceutical Industries Ltd (Israel)

Active Pharmaceutical Ingredients (API) Market Trends:

Market Drivers:

The development in the production of active pharmaceutical ingredients (APIs) and the rising incidence of chronic diseases like cancer and cardiovascular conditions are responsible for the growth. Due to the process's strict adherence to protocol and high capital requirements, many APIs are outsourced to produce APIs. Pharmaceutical firms also gain from outsourcing API production because it eliminates the need for costly manufacturing unit setup and labor. Thus, outsourcing is encouraged by the requirement for cost savings. Over the forecast period, it is anticipated that high prevalence and rising awareness of cardiovascular diseases will propel the segment, driving consumer interest in APIs for cardiology drugs.

Businesses can concentrate on their core competencies thanks to strategic outsourcing, which boosts productivity. Government policies that are supportive of API manufacturing, along with shifting geopolitical conditions, are accelerating market expansion. Demand for personalized medications is anticipated to rise along with the need for targeted therapies using high-potency API compounds, like HPAPI. For instance, ADCs take advantage of antibodies' focus on cancer cells. To affix to the antibody, these cells use linker technology. Since most pharmaceutical companies are pursuing such development programs, it is anticipated that these advanced features of ADCs will drive the market.

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Market Restraints:

Several businesses cannot produce a drug until the drug's patent expires. Thus, several factors cause the patents on highly expensive drugs to expire. This inhibits market expansion. Due to the process's strict adherence to protocol and high capital requirements, many APIs are outsourced to produce APIs. The economies of low- and middle-income nations cannot support it. Therefore, low- and middle-income nations in Africa, Asia-Pacific, and Latin America have greater demand for inexpensive alternatives.

COVID 19 Analysis

Due to COVID-19's supply chain disruption, the API market has undergone significant changes. The governments of numerous nations have also developed plans and provided incentives to encourage the manufacture of API. The global APIs market benefited from the COVID-19 pandemic. The pharmaceutical sector was key in treating COVID-19 symptoms like high fever, cough, and cold. After the COVID-19 outbreak was classified as a pandemic by the World Health Organization, a wide range of renowned drugs, biopharmaceutical companies, and fresh startups stepped forward to develop treatments for the virus. However, the coronavirus breakout has disrupted international trade and the economy. On the market for active pharmaceutical ingredients, a brief effect is anticipated.

Active Pharmaceutical Ingredients (API) Market Segmentation

The market includes generic API and branded/innovative API by API formulation.

By application, the market includes cardiovascular disease, oncology, gastrointestinal disorders, neurological disorders, orthopedic disorders, respiratory, and urology.

By manufacturing process, the market includes captive manufacturing and contract manufacturing.

By type of synthesis, the market includes synthetic and biotech.

By molecules, the market includes large molecules and small molecules.

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Active Pharmaceutical Ingredients Market Regional Insights

The advancements in medical diagnosis brought on by the rise in the incidence of persistent illnesses and other neurological disorders were accounted for by the North American market. The second-biggest market share belongs to the pharmaceutical active ingredient market in Europe. The industry is anticipated to be driven by the increase in research money and the regional presence of major market players. More biopharmaceutical companies are operating in Europe as a result of increased investments. Additionally, the UK active pharmaceutical ingredients market had the fastest growth rate in the European region, while Germany's active pharmaceutical ingredients market had the largest market share.

Due to the prevalence of quickly developing marketplaces like India, China, and South Korea, which have become major hubs for outsourcing drug manufacturing, the Asia-Pacific Active Pharmaceutical Ingredients Market is anticipated to grow at the fastest CAGR from 2022 to 2030. The region benefits from economies like China and India, which the rest of the world depends on for manufacturing APIs at a lower price. Rising healthcare spending in the area is anticipated to drive market expansion.

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