New York, USA, May 04, 2023 (GLOBE NEWSWIRE) -- Diabetic Neuropathic Pain Market to Proliferate, Assesses DelveInsight | Key Companies Active in the Domain - AstraZeneca, Eli Lilly and Company, Eisai, Helixmith, Lexicon, NeurogesX, Centrexion, Pure Green Pharmaceuticals
The increasing prevalence of diabetes patients, rise in screening for pain among diabetics, increase in the geriatric population, and launch of newly approved drugs is likely to fuel the growth of the diabetic neuropathic pain market size during the forecast period (2023–2032).
DelveInsight’s Diabetic Neuropathic Pain Market Insights report includes a comprehensive understanding of current treatment practices, diabetic neuropathic pain emerging drugs, market share of individual therapies, and current and forecasted market size from 2019 to 2032, segmented into 7MM [the United States, the EU-4 (Italy, Spain, France, and Germany), the United Kingdom, and Japan].
Key Takeaways from the Diabetic Neuropathic Pain Market Report
- As per DelveInsight analysis, the diabetic neuropathic pain market is expected to grow positively owing to several underline factors during the study period (2019–2032).
- DelveInsight’s analysis shows that diabetic neuropathic pain cases show an increasing trend in the forecasted period in the 7MM.
- Leading diabetic neuropathic pain companies such as AstraZeneca, Centrexion Therapeutics, Aptinyx, Pure Green Pharmaceuticals Inc., Eli Lilly and Company, Regenacy Pharmaceuticals LLC, Helixmith Co., Ltd., Vertex Pharmaceuticals Incorporated, Eisai Inc., NeuroBo Pharmaceuticals Inc., Dong-A ST Co., Ltd., Daiichi Sankyo, Inc., NeurogesX, Lexicon Pharmaceuticals, and others are developing novel diabetic neuropathic pain drugs that can be available in the diabetic neuropathic pain market in the coming years.
- Some of the key therapies for diabetic neuropathic pain treatment include MEDI 7352, CNTX6016, NYX2925, CBD/PEA, LY3857210, Ricolinostat, Engensis, VX-548, E2007, DA-9801, DS-5565, Capsaicin Dermal Patch, LY3526318, LX9211, and others.
- Several diabetic neuropathic pain therapies are awaiting approval, while some therapies are in the advanced stages of development.
Discover which therapies are expected to grab the major diabetic neuropathic pain market share @ Diabetic Neuropathic Pain Market Report
Diabetic Neuropathic Pain Overview
Diabetic neuropathic pain is a well-known diabetes consequence and the leading cause of all neuropathic pain. Diabetic neuropathic pain affects almost one-third of all diabetic patients. It is defined as the presence of signs and symptoms of nerve dysfunction in diabetic individuals after all other explanations have been ruled out. Prolonged high blood sugar levels can harm nerves throughout the body, but diabetic neuropathic pain most impact the legs and feet.
Diabetic neuropathic pain is characterized by tingling, burning, sharp, shooting, lancinating feelings, and electric shocks. It is usually classified as moderate to severe, and it is often worse at night, causing sleep disruption. The discomfort might be persistent and accompanied by cutaneous allodynia, which can significantly impact the patient’s quality of life, limiting their capacity to do everyday tasks and negatively impacting their mood. Pain may also be a cause of withdrawal from recreational and social activities, and it may be linked to depression.
Diabetic Neuropathic Pain Epidemiology Segmentation
The diabetic neuropathic pain epidemiology section provides insights into the historical and current diabetic neuropathic pain patient pool and forecasted trends for the seven individual major countries. It helps recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders.
The diabetic neuropathic pain market report proffers epidemiological analysis for the study period 2019–2032 in the 7MM segmented into:
- Total Diabetic Neuropathic Pain Prevalent Cases
- Diabetic Neuropathic Pain Diagnosed and Treatable Cases
- Diabetic Neuropathic Pain Gender-specific Cases
- Diabetic Neuropathic Pain Type-specific Cases
Download the report to understand which factors are driving diabetic neuropathic pain epidemiology trends @ Diabetic Neuropathic Pain Epidemiological Insights
Diabetic Neuropathic Pain Treatment Market
Current diabetic neuropathic pain treatment has two key goals: to target the underlying pathophysiological processes to avoid nerve fiber loss and reduce the unpleasant symptoms of PDN to normalize physical and psychological functioning. Tricyclic agents (TCAs), serotonin-norepinephrine reuptake inhibitors (SNRIs), or -aminobutyric acid (GABA) analogs (gabapentin or pregabalin) are commonly recommended as first-line medications, followed by opioids and topical therapies. Diabetic neuropathic pain is typically treated with TCAs, SNRIs, and GABA analogs.
In September 2004, the SNRI duloxetine (Cymbalta, Eli Lilly) was licensed as the first medicine to treat the neuropathic pain associated with diabetic neuropathic pain. Duloxetine inhibits neuronal serotonin and norepinephrine reuptake. Although the specific mechanism of action of the drug’s central pain-inhibitory effect is unknown, it is thought to be connected to the potentiation of serotonergic and noradrenergic activity in the CNS. Blocking norepinephrine reuptake, in particular, has been shown to help with neuropathic pain.
Since the 1960s, traditional anticonvulsants have been utilized to treat neuropathy. However, in 2004, the FDA approved newer anticonvulsants, such as pregabalin, to treat DPN’s neuropathic pain. Because of its effectiveness in lowering pain and pain-related sleep disturbance, AAN guidelines recommend pregabalin as the first-line therapy for diabetic neuropathic pain treatment. Japan’s PMDA approved Mirogabalin for diabetic neuropathic pain treatment in 2019. Daiichi Sankyo is undertaking clinical research for Mirogabalin in the United States, with a planned launch within the study period.
To know more about diabetic neuropathic pain treatment, visit @ Diabetic Neuropathic Pain Treatment Drugs
Key Diabetic Neuropathic Pain Therapies and Companies
- MEDI 7352: AstraZeneca
- CNTX6016: Centrexion Therapeutics
- NYX2925: Aptinyx
- CBD/PEA: Pure Green Pharmaceuticals Inc.
- LY3857210: Eli Lilly and Company
- Ricolinostat: Regenacy Pharmaceuticals LLC
- Engensis: Helixmith Co., Ltd.
- VX-548: Vertex Pharmaceuticals Incorporated
- E2007: Eisai Inc.
- DA-9801: NeuroBo Pharmaceuticals Inc./Dong-A ST Co., Ltd.
- DS-5565: Daiichi Sankyo, Inc.
- Capsaicin Dermal Patch: NeurogesX
- LY3526318: Eli Lilly and Company
- LX9211: Lexicon Pharmaceuticals
Learn more about the FDA-approved drugs for diabetic neuropathic pain @ Drugs for Diabetic Neuropathic Pain Treatment
Diabetic Neuropathic Pain Market Dynamics
The diabetic neuropathic pain market is expected to change in the coming years. One of the primary aspects recognized to influence the growth of the neuropathic pain market is the discovery of new medications for the treatment of neuropathic and chronic pains. Companies are focused on clinical studies to find therapies to treat diabetic neuropathic pain effectively. For example, Eli Lilly produced duloxetine (LY248686) for diabetic peripheral neuropathic pain (DPNP), while Daichi developed mirogabalin for DPNP. Another factor driving the expansion of the diabetic peripheral neuropathic pain market is the development of point-of-care diagnostics to identify and evaluate diabetic peripheral neuropathic pain. DPNCheck by NeuroMetrix, for example, is a rapid, accurate, and quantitative nerve conduction test used to examine nerves to detect, stage, and monitor neuropathy objectively.
Moreover, the diabetic neuropathic pain pipeline is highly robust; many possible therapies are being studied for diabetic neuropathic pain treatment, and it is safe to assume that the therapeutic space will substantially impact the diabetic neuropathic pain market throughout the forecast period. Furthermore, the expected introduction of emerging therapies with improved efficacy, more awareness initiatives programs, and a further improvement in the diagnosis rate will likely boost the growth of the diabetic neuropathic pain market in the 7MM.
However, certain factors may affect the growth of the diabetic neuropathic pain market. The diabetic neuropathic pain market growth may be offset by failures and discontinuation of emerging therapies, unaffordable pricing, market access and reimbursement issues, and a shortage of healthcare specialists. In addition, the undiagnosed, unreported cases and the unawareness about the disease may also impact the diabetic neuropathic pain market growth.
| Report Metrics | Details |
| Study Period | 2019–2032 |
| Coverage | 7MM [The United States, the EU-4 (Germany, France, Italy, and Spain), the United Kingdom, and Japan] |
| Base Year | 2019 |
| Key Diabetic Neuropathic Pain Companies | AstraZeneca, Centrexion Therapeutics, Aptinyx, Pure Green Pharmaceuticals Inc., Eli Lilly and Company, Regenacy Pharmaceuticals LLC, Helixmith Co., Ltd., Vertex Pharmaceuticals Incorporated, Eisai Inc., NeuroBo Pharmaceuticals Inc., Dong-A ST Co., Ltd., Daiichi Sankyo, Inc., NeurogesX, Lexicon Pharmaceuticals, and others |
| Key Diabetic Neuropathic Pain Therapies | MEDI 7352, CNTX6016, NYX2925, CBD/PEA, LY3857210, Ricolinostat, Engensis, VX-548, E2007, DA-9801, DS-5565, Capsaicin Dermal Patch, LY3526318, LX9211, and others |
Scope of the Diabetic Neuropathic Pain Market Report
- Therapeutic Assessment: Diabetic Neuropathic Pain current marketed and emerging therapies
- Diabetic Neuropathic Pain Market Dynamics: Attribute Analysis of Emerging Diabetic Neuropathic Pain Drugs
- Competitive Intelligence Analysis: SWOT analysis and Market entry strategies
- Unmet Needs, KOL’s views, Analyst’s views, Diabetic Neuropathic Pain Market Access and Reimbursement
Discover more about diabetic neuropathic pain drugs in development @ Diabetic Neuropathic Pain Clinical Trials
Table of Contents
| 1. | Diabetic Neuropathic Pain Market Key Insights |
| 2. | Diabetic Neuropathic Pain Market Report Introduction |
| 3. | Diabetic Neuropathic Pain Market Overview at a Glance |
| 4. | Diabetic Neuropathic Pain Market Executive Summary |
| 5. | Disease Background and Overview |
| 6. | Diabetic Neuropathic Pain Treatment and Management |
| 7. | Diabetic Neuropathic Pain Epidemiology and Patient Population |
| 8. | Patient Journey |
| 9. | Diabetic Neuropathic Pain Marketed Drugs |
| 10. | Diabetic Neuropathic Pain Emerging Drugs |
| 11. | Seven Major Diabetic Neuropathic Pain Market Analysis |
| 12. | Diabetic Neuropathic Pain Market Outlook |
| 13. | Potential of Current and Emerging Therapies |
| 14. | KOL Views |
| 15. | Unmet Needs |
| 16. | SWOT Analysis |
| 17. | Appendix |
| 18. | DelveInsight Capabilities |
| 19. | Disclaimer |
| 20. | About DelveInsight |
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