Wilmington, Delaware, Nov. 15, 2023 (GLOBE NEWSWIRE) -- Allied Market Research published a report, titled, “RNA Based Therapeutics Market by Disease Type (RNA antisense and RNA interference (RNAi)), Application (Auto-Immune Disorders and Genetic Disorders) and End User (Hospitals & Clinics and Research Institutes): Global Opportunity Analysis and Industry Forecast, 2021-2030.” According to the report, the global RNA based therapeutics industry is expected to reach $25,121.95 million by 2030, having witnessed a value of $4,938.38 million in 2021, with a considerable CAGR of 17.6% from 2021 to 2030.
Prime Determinants of Market Growth:
The global RNA therapeutics market is driven by the increasing number of government initiatives for large-scale sequencing projects, target specificity, and selectivity of treatment. However, the barriers to drug delivery, high research costs, and the risk of failure limit the market growth. On the other hand, capitalization of the pipeline therapeutics to the market will provide lucrative opportunities for market growth in the coming years.
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The RNA antisense segment to retain its lion’s share throughout the forecast period-
Based on type, the RNA antisense segment accounted for the largest share in 2020, contributing to nearly two-thirds of the global RNA based therapeutics market revenue, and is expected to retain its lion's share throughout the forecast period. Due to the rise in revenue generated from the development and commercialization of RNA antisense drugs and therapeutics. However, the RNA interference (RNAi) segment would display the fastest CAGR of 18.8% from 2021 to 2030.
The genetic disorder segment to rule the roost by 2030-
Based on application, the genetic disorder segment held the major market share in 2020, accounting for more than three-fifths of the global RNA based therapeutics market revenue, and is projected to rule the roost by 2030. The same segment would showcase the highest CAGR of 18.2% from 2021 to 2030. Due to an increase in the incidence of rare diseases, genetic disorders, and molecular diagnosis. The autoimmune disorder segment is also studied in the report.
Recent Developments in the RNA Based Therapeutics Market
- In June 2022, Alnylam Pharmaceuticals, Inc., one of the leading RNAi therapeutics company, announced that the U.S. Food and Drug Administration (FDA) approved AMVUTTRA (vutrisiran), an RNAi therapeutic administered via subcutaneous injection once every three months (quarterly) for the treatment of the polyneuropathy of hereditary transthyretin-mediated (hATTR) amyloidosis in adults.
- In December 2021, Arbutus Biopharma Corporation, a clinical-stage biopharmaceutical company, and Qilu Pharmaceutical, one of the leading pharmaceutical companies in China, announced that the companies have entered into an exclusive licensing agreement and strategic partnership for the development and commercialization of AB-729 for the treatment of hepatitis B. AB-729 is Arbutus’s lead RNA interference (RNAi) therapeutic that is currently in multiple Phase 2a proof-of-concept clinical trials designed to evaluate it in combination with other approved or investigational agents.
- In July 2021, Alnylam and PeptiDream entered into a collaboration agreement to discover and develop peptide-siRNA conjugates for targeted delivery of RNAi therapeutics to a broader range of extrahepatic tissues.
- In August 2021, Genzyme (Sanofi) acquired Translate Bio for the advancement in RNA technology across vaccines and therapeutics development.
- In April 2021, Genzyme (Sanofi) acquired Tidal Therapeutics for the innovative RNA-based research platform with applications in oncology, immunology, and other disease areas.
- In February 2021, the U.S. Food and Drug Administration (FDA) approved AMONDYS 45 (casimersen). AMONDYS 45 is an antisense oligonucleotide from Sarepta’s phosphorodiamidate morpholino oligomer (PMO) platform, indicated for the treatment of Duchenne muscular dystrophy (DMD).
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North America region to dominate its position during the forecast period-
Based on region, North America held the major market share in 2020, holding more than two-fifths the global RNA based therapeutics market revenue, and is expected to continue its dominant position during the forecast period. Due to the prevalence of genetic disorders, the high cost of research and development, the presence of prominent players and their products, and the established healthcare system in the region. However, the Asia-Pacific region would portray the fastest CAGR of 18.9% from 2021 to 2030. Due to the enhancement of research and development facilities, the availability of disposable income, and the rapidly evolving economic conditions.
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Industry-Leading Players: -
- Gradalis, Inc.
- Arrowhead Pharmaceuticals
- Arbutus Biopharma Corporation
- Benitec Biopharma Inc.
- Silence Therapeutics plc
- Alnylam Pharmaceuticals, Inc.
- Genzyme (Sanofi)
- Ionis Pharmaceuticals
- Sarepta Therapeutics
- Biogen, Inc.
The report provides an overview of the leading players in the global RNA based therapeutics market. They have adopted a variety of tactics to expand their presence in the market, such as mergers & acquisitions, novel technological advancements, product launches, and partnerships. The report provides insights into the business performance of each market player, the operating segments they are active in, the product portfolio they have developed, and the trends they confront.
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