MARLBOROUGH, Mass., April 16, 2024 (GLOBE NEWSWIRE) -- Phio Pharmaceuticals Corp. (Nasdaq: PHIO), a clinical stage biotechnology company whose proprietary INTASYL™ siRNA gene silencing technology is designed to make immune cells more effective in killing tumor cells, today announced it is presenting new data about its lead clinical candidate, PH-762, an INTASYL compound. The data will be presented in three posters at the annual meeting of the Society for Investigative Dermatology (SID) on May 16th in Dallas, Texas.
The titles of the three posters are:
- INTASYL Self-delivering RNAi: a Flexible Platform to Treat Dermatological Malignancies
- INTASYL PH-762: Intratumoral Immunotherapy Targeting PD-1
- A Dose-Escalation Study of Intratumoral PH-762 Targeting PD-1 For Cutaneous Carcinoma
PH-762 is currently being studied in a US clinical trial to assess safety and efficacy in specific skin cancers (NCT 06014086). This open-label Phase 1 clinical study is designed to evaluate the safety and tolerability of neoadjuvant use of intratumoral PH-762 in Stages 1, 2, and 4 cutaneous squamous cell carcinoma, Stage 4 melanoma, and Stage 4 Merkel cell carcinoma. Stages 1 and 2 cSCC represent 77% of all new cSCC cases annually.
| Presentation Details are as follows: | ||
| 1. | Title: | INTASYL self-delivering RNAi: A Flexible Platform to Treat Dermatological Malignancies |
| Abstract Number: | 575 | |
| Session Title: | Pharmacology and Therapeutic Development | |
| Presenting Authors: | Melissa Maxwell, Mary Spellman | |
| Session Date/Time: | Thursday, May 16, 4:30-6:30pm | |
| Location: | Trinity Exhibit Hall | |
| 2. | Title: | INTASYL PH-762: Intratumoral immunotherapy targeting PD-1 |
| Abstract Number: | 576 | |
| Session Title: | Pharmacology and Therapeutic Development | |
| Presenting Authors: | Melissa Maxwell, Mary Spellman | |
| Session Date/Time: | Thursday, May 16, 4:30-6:30pm | |
| Location: | Trinity Exhibit Hall | |
| 3. | Title: | Intratumoral PH-762 targeting PD-1 for Cutaneous Carcinoma |
| Abstract Number: | 283 | |
| Session Title: | Clinical Research - Interventional Research | |
| Presenting Authors: | Melissa Maxwell, Mary Spellman | |
| Session Date/Time: | Thursday, May 16, 4:30-6:30pm | |
| Location: | Trinity Exhibit Hall | |
About Phio Pharmaceuticals Corp.
Phio Pharmaceuticals Corp. (Nasdaq: PHIO) is a clinical stage biotechnology company whose proprietary INTASYL™ RNAi technology is designed to make immune cells more effective in killing tumor cells. INTASYL is the only self-delivering RNAi technology focused on immuno-oncology therapeutics. INTASYL drugs precisely target specific proteins that reduce the body’s ability to fight cancer, without the need for specialized formulations or drug delivery systems.
For additional information, visit the Company’s website, www.phiopharma.com.
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Contact:
Phio Pharmaceuticals Corp.
ir@phiopharma.com
PR Contact
Michael Adams
Bridge View Media
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