Dublin, June 07, 2024 (GLOBE NEWSWIRE) -- The "Global Trispecific Antibodies Clinical Trials & Market Outlook 2024" report has been added to ResearchAndMarkets.com's offering.
The blueprint in the domain of immunotherapy has perceived futuristic with the advent of antibody founded therapy, like monospecific and bispecific antibodies, in the past decenniums. The investigation has picked up its gait after the FDA approval of the first monoclonal antibody, rituximab, for the management of patients suffering from non-Hodgkin's lymphoma.
Albeit, the monospecific antibodies have demonstrated gigantic triumph, there comes a number of pitfalls, such as their ability to target only one type of antigens as well as increased therapy resistance, urges the need to develop more therapies that will target more than one antigen or foreign foe inside the person's body.
In recent years, trispecific antibody has emerged as a promising therapeutic target due to its plausibility in targeting 3 antigens at the same time, making it a game changer candidate for intervention in various ailments.
Global Trispecific Antibodies Clinical Trials & Market Outlook 2024 Report Highlights:
- Trispecific Antibodies in Clinical Trials: > 50 Antibodies
- Majority of Antibodies Developed for Multiple Myeloma: 8 Antibodies
- Trispecific Antibodies Clinical Trials Insight by Company, Country, Indication & Phase
- Platforms Used for Pioneering Trispecific Antibody
- China Dominating Trispecific Antibodies Clinical Trials: >20 Antibodies
- Competitive Landscape: Insight on 18 Companies
To date, no trispecific antibody have been launched in the market; however, it is probable that handful of trispecific antibodies will be approved in the imminent years. Founded on the accomplishment of monospecific antibodies, healthcare professionals have developed trispecific antibody, which can simultaneously bind to three different antigens at the same time, enhancing the precision and effectiveness of targeting tumor cells; representing a groundbreaking innovation in the field of cancer immunotherapy.
At present, more than 50 trispecific antibodies are lately in the preclinical together with clinical studies for the treatment of cancer, infectious diseases, and eye diseases. Nevertheless, researchers believed that the clinical conduit of trispecific antibody is proposed to perceive swift development in the years ahead and will likely expand into additional therapeutic areas like autoimmune diseases, and beyond. As progression in trispecific antibody understanding, mode of action in addition to protein engineering innovations upsurges; simultaneously, the unconventional design of trispecific constructs tailored to precise disease biology and molecular mechanisms will expand.
Accompanied that, the presences of giant pharma companies, such as Roche/ Genentech, Chugai Pharmaceutical, Genor Biopharma, Johnson & Johnson, Merck, Gilead Sciences, Xencor, Numab Therapeutics others, signifies that the sector of trispecific antibodies will prosper further in the forthcoming years as the involvement of giant stakeholders aid to conduct multiple research studies.
Over and above, pharmaceutical companies as well as biotechnology corporations are progressively engaging in strategic collaborations, investments, in addition to acquisitions to influence corresponding expertise and resources in trispecific antibody development domain. These partnerships accelerate research and development, optimize clinical trial design, and enhance market penetration. For instance, in May 2024, Merck has acquired EyeBio with an investment of US$ 3 Billion in order to advance the sector of trispecific antibody. Furthermore, Gilead Science and Merus collaboration deal to discover novel antibody-based trispecific t-cell engagers in March 2024 is another such example.
For the treatment of cancer disorders, a diverse landscape of trispecific antibody candidates is currently under evaluation to treat solid tumors and hematological cancer diseases. However, in the recent years, scientists have expanded the clinical application of trispecific antibody beyond cancer and can be utilized to treat other indications such as eye disorders, viral infections and other, specifying novel avenue. Given their biological complexity as well as anticipated premium pricing, the segment of trispecific assets could feasibly generate multi billion-dollar peak sales in forthcoming years among successful programs.
Looking further ahead, the commercial global market of trispecific antibody is intensifying at a farfetched pace owing to the market drivers like the rising population, involvement of stakeholders, ongoing pre-clinical and clinical trials, augment in technological advancement in immunotherapies domain, rise in awareness for immuno oncology therapy, together with increase in investments and licensing deals. Presently, the US as well as China have become the front runner up in the segment of trispecific immuno therapy due to the rising research in addition to clinical trials.
Key Topics Covered:
1. Trispecific Antibody as Targeted Therapy
2. Trispecific Antibody Current Clinical Development & Future Commercialization Outlook
2.1 Current Market Development Scenario
2.2 Future Market Commercialization Outlook
3. Trispecific Antibody Clinical & Market Development Trend Analysis by Region
3.1 US
3.2 China
3.3 EU
3.4 UK
3.5 Japan
3.6 Australia
4. Trispecific Antibodies Therapeutic Clinical Tends by Indications
4.1 Cancer
4.1.1 Breast Cancer
4.1.2 Colorectal Cancer
4.1.3 Lung Cancer
4.1.4 Multiple Myeloma
4.1.5 Lymphoma
4.1.6 Leukemia
4.2 Viral Infections
4.3 Eye Diseases
5. Global Trispecific Antibodies Clinical Trials Overview
5.1 By Country
5.2 By Phase
5.3 By Company
5.4 By Indication
5.5 By Patient Segment
6. Global Trispecific Antibodies Clinical Trials Insight by Company, Country, Indication & Phase
6.1 Research
6.2 Preclinical
6.3 Phase I
6.4 Phase I/II
7. Trispecific Antibody Market Dynamics
7.1 Market Drivers
7.2 Market Challenges
8. Recent Trends in Trispecific Antibody Market: Partnerships, Acquisitions, Collaboration, & Investments
9. Combinations Approaches for Bourgeoning Trispecific Antibody
9.1 Immunotherapy
9.2 Radiotherapy
10. Platforms Used for Pioneering Trispecific Antibody
10.1 Tavotek Biotherapeutics - TavoSelect Platform
10.2 Tavotek Biotherapeutics - TavoPrecise Platform
10.3 Purple Biotech - Tribody Antibody Platform
10.4 Simcere Zaiming's - T-Cell Engager Polyspecific Antibody Technology Platform
10.5 Ichnos Sciences - BEAT Platform
10.6 Molecular Partners - DARPin Platform
10.7 Merus - Triclonics Platform
11. Competitive Landscape
11.1 AbbVie
11.2 Antibody Studio
11.3 Beijing Mabworks Biotech
11.4 Biocytogen Pharmaceuticals
11.5 Chimagen Biosciences
11.6 Chiome Bioscience
11.7 Genor Biopharma
11.8 GT Biopharma
11.9 Harpoon Therapeutics
11.10 Ichnos Sciences
11.11 KisoJi Biotechnology
11.12 L and L Biopharma
11.13 Lyvgen Biopharma
11.14 Numab
11.15 OPKO Health
11.16 Sanofi
11.17 Sichuan Baili Pharmaceuticals
11.18 TG ImmunoPharma
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