Global Upstream Bioprocessing Market Analysis Report 2024-2030: A $59.24 Billion Market by 2030, Registering a CAGR of 14.3% from 2024 to 2030

Dublin, June 11, 2024 (GLOBE NEWSWIRE) -- The "Global Upstream Bioprocessing Market Size, Share & Trends Analysis Report by Product (Bioreactors/Fermenters, Cell Culture Products), Workflow (Media Preparation, Cell Culture), Use Type (Multi-use, Single-use), Mode, Region, and Segment Forecasts, 2024-2030" report has been added to's offering.

The global upstream bioprocessing market size is expected to reach USD 59.24 billion by 2030, registering a CAGR of 14.3% from 2024 to 2030.

Commercial success and wide acceptance of biopharmaceuticals have provided lucrative growth avenues to several in house as well as contract manufacturing biopharmaceutical companies. Furthermore, a confluence of factors, such as high demand for biosimilars and biologics, launch of improved cost-effective technologies, and growing acceptance of single-use systems have driven the revenue performance of the market.

Start-ups and new market entrants often face budget constraints while establishing new biomanufacturing plants. Thus, these entities expand their biotherapeutics portfolio by outsourcing the production process to contract services, thereby aiding in revenue growth for upstream bioprocessing services.

Continuous upstream bioprocessing has greatly benefited the bioprocessing industry. Rising implementation of methods, such as acoustic wave technology and continuous centrifugation, for clarification of bioreactor cultures tends to minimize the clarification burden. This, in turn, increases the cell-culture densities, consequently resulting in efficient upstream processes.

Ongoing advancements in cell line productivity with respect to protein expression and clone screening are expected to result in the fastest CAGR of cell culture products over the forecast period. Cell culture is considered as the most challenging and crucial step in upstream bioprocessing, and thus demands more attention with respect to technological intricacies, resulting in the largest share in the upstream bioprocessing market.

Factors such as multi-use systems incur one-time investment, are applicable for larger bioprocessing volumes and maintain the pH and oxygen accurately resulting in high usage rate of these systems. However, a paradigm shift from conventional stainless-steel bioreactors to single-use bioreactor systems has attributed to the lucrative growth of the single-use segment.

Key market players are adopting strategic initiatives, such as novel product developments, mutually beneficial partnerships, agreements, and geographical expansion to reinforce their market presence. For instance, in February 2019, Danaher Corporation signed an agreement to acquire the Biopharma business of GE Life Sciences. The acquisition broadened Danaher's market presence with the addition of GE Biopharma's cell culture media, single-use technologies, development instrumentation, and consumables to its existing portfolio.

Upstream Bioprocessing Market Report Highlights

  • High availability of bioreactors and continuous launches of single-use bioreactors by the key market players can be attributed to the remarkable revenue share of the bioreactors segment
  • Presence of well-established biopharmaceutical manufacturing firms capable of performing in-house bioproduction has led to the maximum revenue share of this segment
  • The outsourced segment is expected to grow at the highest CAGR over the forecast period, owing to increase in investments and expansion of manufacturing capabilities through the integration of single-use systems in the plants by CMOs
  • North America dominated the market and accounted for a share of 36.2% in 2023 as a result of the continuous innovations in biotechnology and rising preferences for biopharmaceuticals in the region. Moreover, the presence of substantial in-house biopharmaceutical manufacturers coupled with numerous investments in the U.S. biologics market has driven the growth
  • Asia Pacific is expected to be the fastest-growing region in the market and is expected to grow at a CAGR of 17.4% during the forecast period due to growing awareness about the rapid analytical methods that can be used for in-process control during the upstream workflows

Key Topics Covered:

Chapter 1. Upstream Bioprocessing Market: Methodology and Scope

Chapter 2. Upstream Bioprocessing Market: Executive Summary
2.1. Market Outlook
2.2. Segment Outlook
2.3. Competitive Insights

Chapter 3. Upstream Bioprocessing Market: Variables, Trends & Scope
3.1. Market Lineage Outlook
3.2. Market Dynamics
3.3. Upstream Bioprocessing Market Analysis Tools

Chapter 4. Upstream Bioprocessing Market: Product Estimates & Trend Analysis
4.1. Segment Dashboard
4.2. Global Upstream Bioprocessing Market Product Movement Analysis
4.3. Global Upstream Bioprocessing Market Size & Trend Analysis, by Product, 2018 to 2030 (USD Million)
4.4. Bioreactors/Fermenters
4.4.1. Bioreactors/fermenters Market Estimates and Forecasts 2018 to 2030 (USD Million)
4.5. Cell Culture Products
4.6. Filters
4.7. Bioreactors Accessories
4.8. Bags & Containers
4.9. Others

Chapter 5. Upstream Bioprocessing Market: Workflow Estimates & Trend Analysis
5.1. Segment Dashboard
5.2. Global Upstream Bioprocessing Market Workflow Movement Analysis
5.3. Global Upstream Bioprocessing Market Size & Trend Analysis, by Workflow, 2018 to 2030 (USD Million)
5.4. Media Preparation
5.5. Cell Culture
5.6. Cell Separation

Chapter 6. Upstream Bioprocessing Market: Use Type Estimates & Trend Analysis
6.1. Segment Dashboard
6.2. Global Upstream Bioprocessing Market Use Type Movement Analysis
6.3. Global Upstream Bioprocessing Market Size & Trend Analysis, by Use Type, 2018 to 2030 (USD Million)
6.4. Multi-use
6.5. Single-use

Chapter 7. Upstream Bioprocessing Market: Mode Estimates & Trend Analysis
7.1. Segment Dashboard
7.2. Global Upstream Bioprocessing Market Mode Movement Analysis
7.3. Global Upstream Bioprocessing Market Size & Trend Analysis, by Mode, 2018 to 2030 (USD Million)
7.4. In-house
7.5. Outsourced

Chapter 8. Upstream Bioprocessing Market: Regional Estimates & Trend Analysis
8.1. Regional Market Share Analysis, 2023 & 2030
8.2. Regional Market Dashboard
8.3. Market Size, & Forecasts Trend Analysis, 2018 to 2030:

Chapter 9. Competitive Landscape
9.1. Company/Competition Categorization
9.2. Strategy Mapping
9.3. Company Market Position Analysis, 2023
9.4. Company Profiles/Listing

  • Thermo Fisher Scientific, Inc.
  • Merck KGaA
  • Corning Incorporated
  • Sartorius AG
  • Eppendorf AG
  • Danaher
  • Boehringer Ingelheim GmbH
  • Applikon Biotechnology
  • PBS Biotech, Inc.
  • Lonza
  • VWR International, LLC
  • Meissner Filtration Products, Inc.
  • Repligen Corporation
  • Entegris
  • Kuhner AG

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