Contact Information: Contacts: Kevin Krenitsky Chief Executive Officer BioServe 301-470-3362 Constantine Theodoropulos Boston Communications 617-292-7319
BioServe Announces ControlMATCH for More Efficient Biomarker Validation
New Line of DNA and Serum Samples for Type II Diabetes, Hypertension and Hyperlipidemia Provide Researchers Access to Clinically Defined Controls to Validate Biomedical Research Results
| Source: BioServe
BELTSVILLE, MD--(Marketwire - December 4, 2007) - BioServe today introduced ControlMATCH, a new line of fully annotated
control DNA and serum samples designed to help biomedical researchers
efficiently validate new biomarkers and early stage clinical trial drug
candidates. Leveraging BioServe's Global Repository of 600,000 human biological
samples, ControlMATCH allows researchers to select and match control
samples to the specific needs of their own DNA and/or serum-based studies.
ControlMATCH DNA and serum controls will initially cover type II diabetes,
hypertension and hyperlipidemia, and extend to other disease states in
early 2008.
ControlMATCH normal samples for type II diabetes, hypertension and
hyperlipidemia are annotated with body mass index (BMI), confirmed normal
blood glucose levels, confirmed normal blood pressure and cholesterol
levels, and a family history of health status and ethnicity, determined by
data collected on three generations. ControlMATCH therefore permits
researchers to identify one-to-one matched controls for extended criteria
such as age, gender, ethnicity, BMI, diet and a host of lifestyle factors.
Furthermore, ControlMATCH includes clinically confirmed negative results
enabling researchers to further confirm that their markers are valued
against the correct set of controls.
Xin Li Wang, a professor and director in the cardiothoracic research
laboratory in the division of cardiothoracic surgery of the Michael E.
DeBakey Department of Surgery at Baylor College of Medicine, commented, "We
are engaged in landmark cardiothoracic studies that we hope will reveal the
DNA aberrations in a few target genes responsible for thoracic aortic
disease. Like any large epidemiological study, time is money and generating
valid results as quickly as possible is a prerequisite for success."
"The faster a study is able to generate validated results, the higher the
probability of achieving longer term program milestones. By providing us
with ready made DNA samples stratified by age, ethnicity and smoking
status, BioServe's ControlMATCH has proven to be an indispensable tool in
accelerating our research," he added.
"ControlMATCH was developed to be a powerful validation tool for
epidemiologists and researchers investigating a variety of major diseases,"
said Kevin Krenitsky, Chief Executive Officer, BioServe. "DNA and serum
control sets linked to extensive clinical, demographic and lifestyle data
will enable researchers to both rapidly validate which markers are valuable
and worth pursuing, and generally contribute to the genetic understanding
of debilitating disease."
About BioServe
BioServe is a leader
in the processing, development, and validation of diagnostic tests for the
practice of personalized, predictive and preventive medicine. Leading
pharma, biotech and diagnostic firms collaborate with BioServe to identify
and validate markers that cause disease while correlating clinical and
molecular data to develop new diagnostic tests promoting wellness around
the world. BioServe offers the Global Repository®, a growing library of over 600,000
human DNA, tissue and serum samples linked to detailed clinical and
demographic data from 140,000 consented and anonymized patients from four
continents. Leveraging BioServe's robust genomic analytical services, technology, Global Repository and
CLIA-certified laboratory, collaborators gain a complete, highly efficient
platform for processing diagnostic test results and identifying genomic
markers for powerful new assays. BioServe has headquarters in Beltsville,
MD and Hyderabad, India. For more information please visit www.bioserve.com
or call 301-470-3362.