Epilepsy Pipeline: Insights into Novel and Emerging Pipeline Therapies, Key Pharma Players, Clinical Trials, Growth Prospects, and Treatment Landscape | DelveInsight

The Epilepsy Pipeline landscape is evolving with increased insight into biological pathways and mechanisms underlying Epilepsy, leading towards more targeted therapies.


Las Vegas, USA, Oct. 04, 2021 (GLOBE NEWSWIRE) -- Epilepsy Pipeline: Insights into Novel and Emerging Pipeline Therapies, Key Pharma Players, Clinical Trials, Growth Prospects, and Treatment Landscape | DelveInsight

The Epilepsy Pipeline landscape is evolving with increased insight into biological pathways and mechanisms underlying Epilepsy, leading towards more targeted therapies.

DelveInsight’s Epilepsy Pipeline Insight 2021’ report offers exhaustive global coverage of available, marketed, and pipeline therapies under different phases of clinical development, key companies working to advance the pipeline space, and future growth potential of the Epilepsy pipeline domain. 

Some of the essential takeaways from the Epilepsy Pipeline report:

  • DelveInsight’s Epilepsy Pipeline analysis depicts the space with 70+ active players working to develop 70+ pipeline therapies. 
  • Major pharmaceutical companies are developing potential drug candidates to improve the Epilepsy treatment scenario, such as Otsuka Pharmaceutical Co. Ltd, Cerebral Therapeutics LLC, Marinus Pharmaceuticals, Xenon Pharmaceuticals, PTC Therapeutics, Eisai, Longboard Pharmaceuticals, Neurocrine Biosciences, and others.
  • Key Epilepsy pipeline therapies such as OPC-214870, CT-010, Ganaxolone, XEN496, Vatiquinone E-2730, LP352, NBI 827104, and others are under investigation in different phases of clinical trials.
  • In January 2021, Addex Therapeutics announced that its partner Janssen Pharmaceuticals had received FDA’s Investigational New Drug (IND) approval to begin a Phase IIa proof of concept study with the selective metabotropic glutamate type 2 (mGlu2) receptor positive allosteric modulator (PAM), JNJ-40411813 (ADX71149), in patients with Epilepsy.
  • In October 2020, PTC Therapeutics announced the initiation of a registration-directed Phase II/III clinical trial to evaluate vatiquinone (PTC743) in patients with mitochondrial Epilepsy, the highly morbid condition of refractory seizures in children with inherited mitochondrial disease.

Request for Epilepsy sample report to learn more about trends in specific geographies @ Epilepsy Emerging Therapies and Forecast 

The Epilepsy pipeline report lays down detailed profiles of the pipeline assets, inactive and dormant assets, comparative analysis of clinical and non-clinical stage Epilepsy products, comprehensive assessment of driving and restraining factors,  and opportunities as well as risks in the Epilepsy pipeline landscape.

Epilepsy Overview

Epilepsy is a chronic neurological disorder characterized by frequent and recurring seizures leading to unusual behavior. The primary cause of Epilepsy is not clear, but it is noted that any change in the nerve cells, neurons, and the brain resulting in abnormal signals can be the possible reason.

The most common symptom of Epilepsy includes seizures; however, additional symptoms like convulsion without fever, low consciousness, less awareness, loss of taste, smell, sight, hearing, etc., can also be present.

For further information about Epilepsy treatment and pipeline therapies, visit @ Epilepsy Pipeline Assessment 

Epilepsy Pipeline Drugs

DrugCompanyPhaseMoARoA
OPC-214870 Otsuka Pharmaceutical Co. Ltd Phase IAntiepilepticOral
CT-010Cerebral Therapeutics LLCPhase II4-aminobutyrate transaminase inhibitorsIntraventricular
GanaxoloneMarinus PharmaceuticalsPhase IIIGABA A receptor agonistsIntravenous
XEN496Xenon PharmaceuticalsPhase IIIKCNQ potassium channel agonistsOral
Vatiquinone PTC TherapeuticsPhase II/IIINQO1 modulatorsOral
E-2730EisaiPhase IISynaptic transmission modulatorsOral
NBI 827104Neurocrine BiosciencesPhase IIT type calcium channel antagonistsOral

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Epilepsy Therapeutics Assessment

The Epilepsy Pipeline report proffers an integral view of the Epilepsy emerging novel therapies segregated by Stage, Product Type, Route of Administration, Molecule Type, and Mechanism of Action.

By Product Type

  • Mono
  • Combination
  • Mono/Combination

By Stage

  • Discovery 
  • Pre-clinical
  • Phase I
  • Phase II
  • Phase III
  • Pre-registration

By Route of Administration

  • Subcutaneous
  • Intravenous
  • Oral
  • Intraventricular
  • Inhalation

By Molecule Type 

  • Gene therapy
  • Stem cell therapy
  • Small molecules
  • Pyridines

By Mechanism of Action

  • 4-aminobutyrate transaminase inhibitors
  • GABA A receptor agonists
  • KCNQ potassium channel agonists
  • NQO1 modulators
  • Serotonin receptor agonists
  • T type calcium channel antagonists

By Targets

  • GABA A receptor
  • KCNQ potassium channel
  • Serotonin receptor
  • NQO1
  • T type calcium channel 
  • Synaptic transmission

Scope of the Epilepsy Pipeline Report 

  • Coverage: Global 
  • Major Players: Otsuka Pharmaceutical Co. Ltd, Cerebral Therapeutics LLC, Marinus Pharmaceuticals, Xenon Pharmaceuticals, PTC Therapeutics, Eisai, Longboard Pharmaceuticals, Neurocrine Biosciences, and others.
  • Key Epilepsy Pipeline Therapies: OPC-214870, CT-010, Ganaxolone, XEN496, Vatiquinone E-2730, LP352, NBI 827104, and others.

Dive deep into rich insights of Epilepsy novel and emerging drugs and their analysis @ Epilepsy Pipeline Emerging Novel Therapies 

Table of Contents 

1Introduction
2Executive Summary
3Epilepsy: Overview
4Epilepsy - Analytical Perspective In-depth Commercial Assessment
5Pipeline Therapeutics
6Late Stage Products (Phase III)
7Late Stage Products (Phase II/III)
8Mid Stage Products (Phase II)
9Early Stage Products (Phase I)
10Therapeutic Assessment
11Inactive Products
12Company-University Collaborations (Licensing/Partnering) Analysis
13Epilepsy Key Companies
14Epilepsy Key Products
15Epilepsy- Unmet Needs
16Epilepsy- Market Drivers and Barriers
17Epilepsy- Future Perspectives and Conclusion
18Epilepsy Analyst Views
19Appendix
20About DelveInsight

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Track candidate’s clinical development journey here @ Profiling and Comparative Therapeutic Assessment

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  • In the United States, more than 2.5 million people are living with Epilepsy, out of which approximately 1 million continue to experience seizures despite adequate treatment with antiseizure drugs. 

Ever-evolving Market Dynamics of Epilepsy – a silver lining!

  • The major drawback of the current antiepileptic drugs (AEDs) is their modest efficacy even at best; therefore, many patients require as many as four concurrent AEDs and contend with their host of side effects. 

21 of the most common questions about Epilepsy

  • The term Epilepsy isn’t new. It’s been present in the air for centuries now, however, only a few are aware that it is one of the most common neurological diseases in the world.

About DelveInsight

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