Las Vegas, USA, March 10, 2022 (GLOBE NEWSWIRE) -- Adenoid Cystic Carcinoma Pipeline is Indicative of Many Opportunities Left For Research and Development, Analyzes DelveInsight
Adenoid Cystic Carcinoma is a rare and unique form of cancer that is known to be unpredictable in nature, with a typical growth pattern of being slow and gradual, but over time can be progressive, insidious, and relentless. Targeted therapies are being developed and tested in clinical trials that may be useful as a treatment approach for Adenoid Cystic Carcinoma.
DelveInsight’s ‘Adenoid Cystic Carcinoma Pipeline Insight 2022’ report offers exhaustive global coverage of available, marketed, and pipeline therapies in different phases of clinical development, major pharmaceutical companies working to advance the pipeline space, and future growth potential of the Adenoid Cystic Carcinoma pipeline domain.
Some of the essential takeaways from the Adenoid Cystic Carcinoma Pipeline report:
- DelveInsight’s Adenoid Cystic Carcinoma Pipeline analysis depicts a robust space with 16+ active players working to develop many treatment pipeline therapies.
- Some of the key Adenoid Cystic Carcinoma companies working to develop potential drug candidates to improve the Adenoid Cystic Carcinoma treatment scenario include SHEPHERD Therapeutics, Amgen, CureVac AG, Elevar Therapeutics, Actuate Therapeutics, Ayala Pharmaceuticals, Prelude Therapeutics, Merck Sharp & Dohme Corp., Lilly USA, LLC, Celgene Corporation, Eisai Inc., Bayer AG, CELLESTIA BIOTECH SA, Boston Biomedical, OncoMed Pharmaceuticals, Sumitomo Dainippon Pharma Co., Ltd., and many others.
- Essential Adenoid Cystic Carcinoma pipeline therapies such as Research program cancer therapeutics, AMG 232, CV8102, Rivoceranib, Elraglusib, AL101, PRT543, and others are under development in different phases of clinical trials.
- In September 2021, Ayala Pharmaceuticals announced new preliminary clinical data from the 6mg cohort of its ongoing Phase 2 ACCURACY trial of AL101 for recurrent/metastatic Adenoid Cystic Carcinoma treatment harboring Notch-activating mutations.
- In February 2021, the US FDA granted Orphan Drug Designation to the small molecule tyrosine kinase inhibitor apatinib (Rivoceranib) for the treatment of rare cancer adenoid cystic carcinoma.
- Prelude Therapeutics is evaluating PRT543 in Phase I clinical trial in advanced solid tumors and select myeloid malignancies, including adenoid cystic carcinoma (ACC), myelofibrosis (MF), genomically-selected myelodysplastic syndrome (MDS), and homologous recombination deficient (HRD+) tumors.
- In November 2021, CureVac announced that Oncology Candidate CV8102 Showed Systemic Immune Response when studied in Phase I clinical trials.
- CV8102 is a single-stranded non-coding RNA optimized to maximize the activation of cellular receptors that normally detect viral pathogens entering the cells. It is currently being evaluated in Phase I clinical stage.
Request a sample and discover more about the report offerings @ Adenoid Cystic Carcinoma Emerging Therapies
The Adenoid Cystic Carcinoma pipeline report lays down detailed profiles of the pipeline assets, comparative analysis of clinical and non-clinical stage Adenoid Cystic Carcinoma products, inactive and dormant assets, comprehensive assessment of driving and restraining factors, as well as the opportunities and risks in the Adenoid Cystic Carcinoma pipeline landscape.
Adenoid Cystic Carcinoma Overview
Adenoid Cystic Carcinoma is a relatively rare form of cancer that most commonly develops in the salivary glands or other regions of the head and neck. Adenoid Cystic Carcinoma can occur in other parts of the body, such as the breast, skin, cervix in females, prostate gland in males, and various other areas. The exact cause of Adenoid Cystic Carcinoma is unknown. However, current research suggests that genetic changes (mutations) are the underlying basis of cellular malignant transformation in many cancers including Adenoid Cystic Carcinoma.
Find out more about the disease and recent developments @ Adenoid Cystic Carcinoma Pipeline Assessment
Adenoid Cystic Carcinoma Pipeline Drugs
| Drug | Company | Phase | MoA | RoA |
| Research program cancer therapeutics | SHEPHERD Therapeutics | Discovery | NA | NA |
| PRT543 | Prelude Therapeutics | Phase I | PRMT5 protein inhibitors | Oral |
| CV8102 | CureVac AG | Phase I | Toll-like receptor 7 agonists | Intratumoral |
| Rivoceranib | Elevar Therapeutics | Phase II | Vascular endothelial growth factor receptor-2 antagonists | Oral |
| Elraglusib | Actuate Therapeutics | Phase II | Glycogen synthase kinase 3 beta inhibitors | Intravenous |
| AL101 | Ayala Pharmaceuticals | Phase II | Amyloid precursor protein secretase inhibitors | Intravenous |
Learn more about the novel and emerging Adenoid Cystic Carcinoma pipeline therapies @ Adenoid Cystic Carcinoma Pipeline Analysis
Adenoid Cystic Carcinoma Therapeutics Assessment
The Adenoid Cystic Carcinoma Pipeline report proffers an integral view of the Adenoid Cystic Carcinoma emerging novel therapies segmented by Stage, Product Type, Molecule Type, Mechanism of Action and Route of Administration.
Scope of the Adenoid Cystic Carcinoma Pipeline Report
- Coverage: Global
- Therapeutic Assessment By Adenoid Cystic Carcinoma Product Type: Mono, Combination, Mono/Combination
- Therapeutic Assessment By Adenoid Cystic Carcinoma Clinical Trial Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III, Pre-registration, Inactive candidates
- Therapeutics Assessment By Adenoid Cystic Carcinoma Therapeutics Route of Administration: Oral, Intravenous, Inhalation, Subcutaneous
- Therapeutics Assessment By Adenoid Cystic Carcinoma Therapies Molecule Type: Gene therapy, Stem cell therapy, Small molecules
- Therapeutics Assessment By Adenoid Cystic Carcinoma Therapies Mechanism of Action: Amyloid precursor protein secretase inhibitors, Proto-oncogene protein c mdm2 inhibitors, DDX58 protein stimulants, Toll-like receptor 7 agonists, Amyloid precursor protein secretase inhibitors, Vascular endothelial growth factor receptor-2 antagonists
- Key Adenoid Cystic Carcinoma Companies: SHEPHERD Therapeutics, Amgen, CureVac AG, Elevar Therapeutics, Actuate Therapeutics, Ayala Pharmaceuticals, Prelude Therapeutics, Merck Sharp & Dohme Corp., Lilly USA, LLC, Celgene Corporation, Eisai Inc., Bayer AG, CELLESTIA BIOTECH SA, Boston Biomedical, OncoMed Pharmaceuticals, Sumitomo Dainippon Pharma Co., Ltd., and many others.
- Key Adenoid Cystic Carcinoma Pipeline Therapies: Research program cancer therapeutics, AMG 232, CV8102, Rivoceranib, Elraglusib, AL101, PRT543, and others
Dive deep into rich insights for emerging therapies and assessment, visit @ Adenoid Cystic Carcinoma Emerging Therapies
Table of Contents
| 1 | Introduction |
| 2 | Executive Summary |
| 3 | Adenoid Cystic Carcinoma: Overview |
| 4 | Pipeline Therapeutics |
| 5 | Late Stage Products (Phase III) |
| 6 | Mid Stage Products (Phase II) |
| 6.1 | AL101: Ayala Pharmaceuticals |
| 7 | Early Stage Products (Phase I) |
| 7.1 | CV8102: CureVac AG |
| 8 | Preclinical Stage Products |
| 8.1 | AMG 232 : Amgen |
| 9 | Discovery Stage Products |
| 10 | Therapeutic Assessment |
| 11 | Inactive Products |
| 12 | Collaborations Assessment- Licensing / Partnering / Funding |
| 13 | Adenoid Cystic Carcinoma- Unmet Needs |
| 14 | Adenoid Cystic Carcinoma- Market Drivers and Barriers |
| 15 | Appendix |
| 16 | About DelveInsight |
For further information on the Adenoid Cystic Carcinoma current pipeline therapeutics, reach out @ Adenoid Cystic Carcinoma Ongoing Clinical Trials
Track and assess a candidate’s clinical development journey through Actionable Intelligence and Comparative Therapeutic Assessment
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