New York, USA, Oct. 23, 2023 (GLOBE NEWSWIRE) -- Retinal Vein Occlusion Market to Exhibit Considerable Growth at a CAGR of ~6% During the Study Period (2019–2032) | DelveInsight
The increasing diagnosed prevalence, and the development of well-designed, randomized, controlled non-crossover trials with the potential benefits for RVO patients will drive the retinal vein occlusion market growth in the forecast period (2023–2032).
DelveInsight’s Retinal Vein Occlusion Market Insights report includes a comprehensive understanding of current treatment practices, retinal vein occlusion emerging drugs, market share of individual therapies, and current and forecasted retinal vein occlusion market size from 2019 to 2032, segmented into 7MM [the United States, the EU-4 (Italy, Spain, France, and Germany), the United Kingdom, and Japan].
Key Takeaways from the Retinal Vein Occlusion Market Report
- As per DelveInsight’s analysis, the retinal vein occlusion market size was found to be USD 2.3 billion in 2021 in the 7MM and it is anticipated to grow at a significant CAGR by 2032.
- As per DelveInsight estimates, in the year 2021, the total prevalent cases of retinal vein occlusion were approximately 2.7 million cases in the 7MM, which are expected to increase by 2032 at the CAGR of 1.0% during the study period (2019–2032).
- Leading retinal vein occlusion companies such as Taiwan Liposome Company, Aerie Pharmaceuticals, Graybug Vision, Outlook Therapeutics, Kodiak Sciences Inc, Roche, Chugai Pharmaceuticals, and others are developing novel retinal vein occlusion drugs that can be available in the retinal vein occlusion market in the coming years.
- Some of the key therapies for retinal vein occlusion treatment include TLC399 (ProDex), AR-1105, GB-102 (sunitinib/sunitinib malate), ONS-5010/Lytenava(bevacizumab-vikg), KSI-301, Vabysmo (faricimab), and others.
Discover which therapies are expected to grab the major retinal vein occlusion market share @ Retinal Vein Occlusion Market Report
Retinal Vein Occlusion Overview
Retinal vein occlusion (RVO) stands as the second most prevalent retinal vascular disorder, following diabetic retinopathy. It results from an obstruction in the retinal venous system due to thrombus formation and can affect the central, hemi-central, or branch retinal vein. The primary causative factor is often compression by nearby atherosclerotic retinal arteries. Additionally, other potential causes include external compression or vein wall diseases like vasculitis.
The main indicator is a sudden alteration in vision. This might manifest as blurred vision or a partial or complete loss of sight. The continuous presence of bruising and swelling in the macula is linked to a permanent loss of central vision. This swelling results from damaged blood vessels that release fluid. Typically, these symptoms manifest in one eye, are frequently painless, and can be either temporary or permanent, contingent upon the patient's promptness in seeking treatment and their overall health.
When examining a patient with RVO, it is crucial to undertake a comprehensive evaluation of their adult medical eye health, with particular attention to elements related to retinal vascular diseases. Various diagnostic tests, including Optical Coherence Tomography (OCT) and Fluorescein Angiography (FA), are employed for RVO diagnosis. Additionally, systemic evaluation is often carried out in patients with CRVO, and the direction of this evaluation is determined by the patient's age, concurrent risk factors, and medical history.
Retinal Vein Occlusion Epidemiology Segmentation
The retinal vein occlusion epidemiology section provides insights into the historical and current retinal vein occlusion patient pool and forecasted trends for the 7MM. It helps recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders.
The retinal vein occlusion market report proffers epidemiological analysis for the study period 2019–2032 in the 7MM segmented into:
- Total Retinal Vein Occlusion Prevalent Cases
- Total Retinal Vein Occlusion Diagnosed Prevalent Cases
- Total Retinal Vein Occlusion Gender-specific Diagnosed Prevalent Cases
- Total Retinal Vein Occlusion Age-specific Diagnosed Prevalent Cases
- Retinal Vein Occlusion Type-specific Diagnosed Prevalent Cases
Download the report to understand which factors are driving retinal vein occlusion epidemiology trends @ Retinal Vein Occlusion Epidemiological Insights
Retinal Vein Occlusion Treatment Market
Currently, there is no known remedy to reverse RVO. Individuals afflicted with this condition typically experience enduring alterations in their vision. The primary objective of available treatments is to maintain vision stability by sealing off leaking blood vessels. Key treatments for RVO encompass intravitreal injections of drugs that target vascular endothelial growth factors (VEGF) or corticosteroids designed to combat the growth factors or inflammatory elements that contribute to macular edema. In certain cases where anti-VEGF drugs prove ineffective, intraocular steroid injections may be considered, though they may carry some side effects like increased eye pressure and cataract progression. In challenging situations, laser therapy might be employed in conjunction with anti-VEGF treatment. Pan-retinal laser photocoagulation (PRP) or focal photocoagulation effectively manage neovascularization, preventing neovascularization-related complications in both BRVO and CRVO. Meanwhile, macular laser photocoagulation can address non-ischemic macular edema either as a standalone treatment or in combination with other anti-VEGF or anti-inflammatory medications.
The European Society of Retina Specialists Guidelines suggest that although laser treatment can enhance visual function in cases of macular edema secondary to BRVO, it should be considered a second-line option due to the presence of anti-VEGF therapy alternatives. The US FDA has sanctioned three products for managing macular edema associated with RVO, namely Lucentis (ranibizumab, Roche), Eylea (aflibercept, Regeneron), and Ozurdex (dexamethasone intravitreal implant, AbbVie).
Learn more about the FDA-approved drugs for retinal vein occlusion @ Drugs for Retinal Vein Occlusion Treatment
Key Retinal Vein Occlusion Therapies and Companies
- TLC399 (ProDex): Taiwan Liposome Company
- AR-1105: Aerie Pharmaceuticals
- GB-102 (sunitinib/sunitinib malate): Graybug Vision
- ONS-5010/Lytenava(bevacizumab-vikg): Outlook Therapeutics
- KSI-301: Kodiak Sciences Inc
- Vabysmo (faricimab): Roche/Chugai Pharmaceuticals
To know more about retinal vein occlusion clinical trials, visit @ Retinal Vein Occlusion Treatment Drugs
Retinal Vein Occlusion Market Dynamics
The dynamics of the retinal vein occlusion market are anticipated to change in the coming years. Currently, anti-VEGF drugs are the dominant choice for treating RVO, and this trend is expected to continue in the forecast period. The increasing prevalence of diabetes, lifestyle changes, and a rising incidence of glaucoma, among other factors, are driving the growing use of anti-VEGF drugs in RVO treatment. The expanding elderly population and heightened awareness of eye disorders are expected to increase RVO cases, thereby creating opportunities for new treatment options. Companies can seize the opportunity to meet the unmet needs of RVO patients by offering more durable responses, reduced clinic visits, and improved safety profiles.
However, several factors may impede the growth of the retinal vein occlusion market. Retinal vein occlusion predominantly impacts individuals aged 55 and older, particularly those with underlying high-risk conditions such as diabetes and hypertension. These comorbidities can complicate the treatment approach. Moreover, most currently approved medications do not effectively restore visual function, nor do they directly address the underlying vein blockage. The impending expiration of patents for branded drugs, coupled with the market entry of cost-effective generics and biosimilars, is expected to impede market growth significantly. Additionally, the intricate nature of the disease and the presence of anti-VEGF therapies make it challenging for companies to demonstrate the superior efficacy and added benefits of their drugs compared to existing treatments. For instance, Clearside Biomedical's product Xipere (Suprachoroidal CLS-TA) failed to meet primary endpoints in the Phase III SAPPHIRE trial.
| Retinal Vein Occlusion Report Metrics | Details |
| Study Period | 2019–2032 |
| Retinal Vein Occlusion Report Coverage | 7MM [The United States, the EU-4 (Germany, France, Italy, and Spain), the United Kingdom, and Japan] |
| Retinal Vein Occlusion Market Size in 2021 | USD 2.3 Billion |
| Key Retinal Vein Occlusion Companies | Taiwan Liposome Company, Aerie Pharmaceuticals, Graybug Vision, Outlook Therapeutics, Kodiak Sciences Inc, Roche, Chugai Pharmaceuticals, and others |
| Key Retinal Vein Occlusion Therapies | TLC399 (ProDex), AR-1105, GB-102 (sunitinib/sunitinib malate), ONS-5010/Lytenava(bevacizumab-vikg), KSI-301, Vabysmo (faricimab), and others |
Scope of the Retinal Vein Occlusion Market Report
- Therapeutic Assessment: Retinal Vein Occlusion current marketed and emerging therapies
- Retinal Vein Occlusion Market Dynamics: Attribute Analysis of Emerging Retinal Vein Occlusion Drugs
- Competitive Intelligence Analysis: SWOT analysis and Market entry strategies
- Unmet Needs, KOL’s views, Analyst’s views, Retinal Vein Occlusion Market Access and Reimbursement
Discover more about retinal vein occlusion drugs in development @ Retinal Vein Occlusion Clinical Trials
Table of Contents
| 1. | Retinal Vein Occlusion Market Key Insights |
| 2. | Retinal Vein Occlusion Market Report Introduction |
| 3. | Retinal Vein Occlusion Market Overview at a Glance |
| 4. | Retinal Vein Occlusion Market Executive Summary |
| 5. | Disease Background and Overview |
| 6. | Retinal Vein Occlusion Treatment and Management |
| 7. | Retinal Vein Occlusion Epidemiology and Patient Population |
| 8. | Patient Journey |
| 9. | Retinal Vein Occlusion Marketed Drugs |
| 10. | Retinal Vein Occlusion Emerging Drugs |
| 11. | Seven Major Retinal Vein Occlusion Market Analysis |
| 12. | Retinal Vein Occlusion Market Outlook |
| 13. | Potential of Current and Emerging Therapies |
| 14. | KOL Views |
| 15. | Unmet Needs |
| 16. | SWOT Analysis |
| 17. | Appendix |
| 18. | DelveInsight Capabilities |
| 19. | Disclaimer |
| 20. | About DelveInsight |
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