CEVEC Acknowledges Crucell Claims in Patent Infringement Hearing


LEIDEN, The Netherlands, Dec. 16, 2004 (PRIMEZONE) -- In the patent infringement action initiated by Crucell (Nasdaq:CRXL) against CEVEC Pharmaceuticals GmbH, the German Dusseldorf District Court held a first oral hearing yesterday. CEVEC acknowledged Crucell's claims for an injunction as well as further claims for damages and information.The claims were based on the recently granted European Patent for Crucell's PER.C6(R) technology (EP 833 934). Crucell had argued that CEVEC's cell line N52.E6 constituted an infringement of that patent. The court is expected to render an enforceable interim judgment on the basis of CEVEC's acknowledgement soon.

About Crucell

Crucell N.V. is a biotechnology company focused on developing vaccines and antibodies that prevent and treat infectious diseases, including Ebola, influenza, malaria, West Nile virus and rabies. The company's development programs include collaborations with Aventis Pasteur for influenza vaccines, the U.S. National Institutes of Health for Ebola and malaria vaccines, and GlaxoSmithKline (GSK), Walter Reed Army Institute of Research and New York University for a malaria vaccine. Crucell's products are based on its innovative PER.C6(R) technology, which offers a safer, more efficient way to produce biopharmaceuticals. The company licenses its PER.C6(R) technology to the biopharmaceutical industry on a mostly non-exclusive basis. Licensees and CMO partners include DSM Biologics, GSK, Centocor/J&J and Merck & Co., Inc. Crucell is headquartered in Leiden, The Netherlands, and is listed on the Euronext and NASDAQ stock exchanges (ticker symbol CRXL). For more information, please visit www.crucell.com.

This press release contains forward-looking statements that involve inherent risks and uncertainties. We have identified certain important factors that may cause actual results to differ materially from those contained in such forward-looking statements. For information relating to these factors please refer to our Form 20-F, as filed with the U.S. Securities and Exchange Commission on February 27, 2004, and the section entitled "Risk Factors". The company prepares its financial statements under generally accepted accounting principles in the United States (US GAAP).

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