Smith & Nephew PLC announce - Holding(s) in Company


London, UK -- (MARKET WIRE) -- November 6, 2006 --

                   NOTIFICATION OF MAJOR INTERESTS IN SHARES

6 November 2006

Smith & Nephew plc has been notified today, pursuant to Section 198 of the Companies Act 1985 (as amended), by AXA Investment Managers UK Ltd, that they no longer have a notifiable interest in the issued share capital of the Company.

Name of contact and telephone number for queries

Phil Higgins - Assistant Company Secretary
020 7960 2228
Name and signature of authorised company official responsible for making this notification

Phil Higgins - Assistant Company Secretary

Date of notification

06.11.06

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