Contact Information: Contact information: Thomas D. Ingolia CEO Email Contact 480-385-3800
Health Enhancement Products Announces Final Results of Clinical Trials of ProAlgaZyme in Metabolic Syndrome and HIV Patients
| Source: Health Enhancement Products, Inc.
SCOTTSDALE, AZ -- (MARKET WIRE) -- January 19, 2007 --Health Enhancement Products, Inc. (OTCBB : HEPI ), a Scottsdale Arizona company, announced today the final results of
two clinical trials involving its ProAlgaZyme product (PAZ) conducted by
Dr. Julius Oben, Head of the Laboratory of Nutrition and Nutritional
Biochemistry at the University of Yaounde, Cameroon. One study involved
participants with Metabolic Syndrome, a condition typified by metabolic and
lipid imbalances. Positive results (p=0.05 or better) were seen in the key
prospective markers, including cholesterol levels, cholesterol ratios, and
C-reactive protein levels (a marker of inflammation). The second study
involved patients infected with HIV virus. Patients were broken up into
high and low dose groups. High dose groups showed positive results in the
key prospective markers, including reduction in viral load and increase in
levels of CD4+ cells. (CD4+ cells are white blood cells with important
immune functions; levels of these cells are reduced as a consequence of HIV
infection.) Low dose groups also showed significant increases in the CD4+
levels but did not show reduction in viral load.
Dr. Oben noted, "PAZ appears to have the potential to increase the CD4
T-lymphocyte cell count as well as reduce the concentration of total
cholesterol. The level of significant differences observed between the PAZ
group and the placebo indicates the potential of PAZ in treating
metabolic syndrome as well as immuno-deficient patients." Dr. Tom Ingolia,
CEO of Health Enhancement Products, added that the Company was extremely
encouraged with the results: "The outcome of this study is exceptional,
although it is consistent with what we have heard anecdotally from our
customers. We are more committed than ever to exploring the potential of
this product to enhance the health of our consumers. These results are in
areas of significant medical need and enormous market potential."
Design and Result of Studies
The Metabolic Syndrome trial was a double blinded, placebo-controlled
study. For a period of 10 weeks, 30 participants received one ounce doses
of ProAlgaZyme 4 times per day, and 30 received placebo. Improvements
(p=0.05 or lower) were seen in the key prospective markers, including
C-reactive protein down 57% in the ProAlgaZyme group vs. down 7% in the
placebo group; total cholesterol down 32% in the ProAlgaZyme group vs. down
3% in the placebo group, and HDL ("good cholesterol") levels up 14% in the
ProAlgaZyme group vs. down 8% in the placebo group.
In the HIV Trial, data was collected from 36 patients administered low dose
(4 to 8 ounces of ProAlgaZyme per day) and 19 patients administered high
dose (16 to 20 ounces of ProAlgaZyme per day) for 12 weeks, with no
changes in their previous treatment regimens. In the low and high dose
groups respectively, viral loads were down 15% and 32%; CD4+ T lymphocyte
levels were up 36% and 49%; C-Reactive Protein levels were down 45% and
41%; and Total Cholesterol levels were down 30% and 30%. The reduction in
viral load in the low dose group was not statistically significant; all
other changes were statistically significant (p=0.05 or better).
Details of these studies are included in manuscripts in preparation, and
will be available upon publication.
About Metabolic Syndrome, Cholesterol, and C-Reactive Protein
Metabolic Syndrome, also called Syndrome X, is a collection of symptoms
including metabolic and lipid imbalances. It is estimated that the
condition afflicts about 1 in every 4 persons in the U.S., and as high as 4
out of every 10 individuals aged 60 and above. According the American
Heart Association, Metabolic Syndrome is associated with obesity and Type
II Diabetes. Cardiovascular risk is associated with the imbalances in
cholesterol levels and ratios often seen in the syndrome, with elevated
total cholesterol and low ratios of HDL ("good cholesterol") vs. LDL.
Another marker associated with cardiovascular risk is C-Reactive Protein
(CRP), a blood marker that according to the American Heart Association is
elevated in patients with systemic inflammation and can be used as an
indicator of cardiovascular risk, with low, moderate and high
cardiovascular risk assigned to ranges of CRP.
About Health Enhancement Products, Inc. and ProAlgaZyme
Health Enhancement Products, Inc. is a nutraceutical company engaged in the
development of a Dietary Supplement product using only pure, all-natural
ingredients. The company's sole product is ProAlgaZyme, a liquid product
produced from algae grown in 100% distilled water. The liquid in which the
algae are grown is drawn off, filtered, tested and bottled as ProAlgaZyme.
Except for any historical information, the matters discussed in this press
release contain forward-looking statements within the meaning of Section
27A of the Securities Act of 1933 and Section 21E of the Securities
Exchange Act of 1934. These forward-looking statements involve risks and
uncertainties. A number of factors could cause actual results to differ
from those indicated in the forward-looking statements, including future
clinical trial results being different than the company's results to date
and the company's ability to fund its operations and market and sell its
ProAlgaZyme product. Such statements are subject to a number of
assumptions, risks and uncertainties. Readers are cautioned that such
statements are not guarantees of future performance and that actual results
or developments may differ materially from those set forth in the
forward-looking statements. The company undertakes no obligation to
publicly update or revise forward-looking statements, whether as a result
of new information or otherwise.
For more information, please visit www.heponline.com.