Novogen Signs Spanish Patent License With Laboratorios Casen-Fleet

STAMFORD, CT and SYDNEY, AUSTRALIA--(Marketwire - June 23, 2008) - Novogen Limited (ASX: NRT) (NASDAQ: NVGN), the registered owner of the European Patent "Use of isoflavone phyto-oestrogen extracts of soy or clover (EPO 656786 B1), has reached an Agreement with Laboratorios Casen-Fleet for a license in Spain to the Novogen Patent.

Laboratorios Casen-Fleet, the Spanish affiliate of the US multinational healthcare company Fleet Laboratories, has recently acquired the red clover isoflavone-based menopause product Fitogyn from Laboratorios Gynea S.A. In conjunction with the product acquisition Laboratorios Casen Fleet and Novogen have agreed on confidential terms for a Patent License Agreement.

The Chief Executive of Novogen, Mr. Christopher Naughton, said Novogen was dedicated to the development of isoflavonoid technology, protected by intellectual property, in both the dietary supplement and prescription pharmaceutical arenas. In Europe Novogen has negotiated Patent License Agreements with Laboratorios Casen-Fleet and Melbrosin International (manufacturer of Menoflavon).

Novogen's patented dietary supplement products are Promensil, for women's health including the relief of menopausal symptoms, and Trinovin, for prostate health. These brands are marketed directly by Novogen in Australia, Canada and UK, and under license to distributors in the USA, Europe, South East Asia and South Africa.

"Since 2005 Novogen has successfully enforced its isoflavone patent portfolio against USA companies such as GNC, NBTY Inc., Natural Alternatives International Inc, Swanson Health Products and Chattem Inc and Canadian companies such as Swiss Herbal, Sante Naturelle and Genuine Health," said Mr. Naughton.

About Novogen

Novogen Limited is an Australian biotechnology company that has patented isoflavone technology for the treatment and prevention of degenerative diseases and disorders. Over the past ten years, Novogen has conducted the largest and most comprehensive isoflavone clinical testing programs in the world. Novogen is involved in drug discovery and product development for disorders that are commonly associated with aging and coordinates an international clinical research and development program with external collaborators, hospitals and universities.

Novogen's investigational anti-cancer drug phenoxodiol is currently in Phase III human clinical trials in the US, Europe and Australia. The rights to commercialise this drug are licensed to the Company's majority owned subsidiary, Marshall Edwards, Inc., (NASDAQ: MSHL). More information can be found at www.novogen.com and www.marshalledwardsinc.com.

Statements included in this press release that are not historical in nature are "forward-looking statements" within the meaning of the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995. You should be aware that our actual results could differ materially from those contained in the forward-looking statements, which are based on management's current expectations and are subject to a number of risks and uncertainties, including, but not limited to, our failure to successfully commercialize our product candidates; costs and delays in the development and/or FDA approval, or the failure to obtain such approval, of our product candidates; uncertainties in clinical trial results; our inability to maintain or enter into, and the risks resulting from our dependence upon, collaboration or contractual arrangements necessary for the development, manufacture, commercialization, marketing, sales and distribution of any products; competitive factors; our inability to protect our patents or proprietary rights and obtain necessary rights to third party patents and intellectual property to operate our business; our inability to operate our business without infringing the patents and proprietary rights of others; general economic conditions; the failure of any products to gain market acceptance; our inability to obtain any additional required financing; technological changes; government regulation; changes in industry practice; and one-time events. We do not intend to update any of these factors or to publicly announce the results of any revisions to these forward-looking statements.

Contact Information: FOR FURTHER INFORMATION: CHRISTOPHER NAUGHTON MANAGING DIRECTOR NOVOGEN LIMITED TEL 011 61 2 9878 0088 http://www.novogen.com ISSUED BY: WHITECOAT STRATEGIES CONTACT: DAVID SHEON 202 470-2880