Announcement of topline results from the GLACIER study

BI-204 did not meet the primary end-point
Lund, Sweden – 11 July 2012 – BioInvent International AB (OMXS: BINV) today
announced data from the GLACIER phase IIa study evaluating BI-204 in patients
with stable atherosclerotic vascular disease. BioInvent is developing BI-204 in
collaboration with Genentech, a member of the Roche Group (SIX: RO, ROG; OTCQX:
RHHBY).

In the study, BI-204 was administered either as a single dose or in multiple
doses over a twelve week period in addition to standard-of-care. The primary
endpoint of the study was the relative change in inflammatory activity in an
index arterial vessel after twelve weeks, as measured by FDG-PET/CT imaging
([18F]-2-deoxyglucose positron emission-tomography/computed tomography). No
statistically significant reduction between placebo and the two active treatment
arms was observed. Thus, the study did not meet its primary endpoint.

Based on preliminary safety data review, BI-204 was well-tolerated and no drug
-related safety signals were identified. An analysis of additional safety and
efficacy data will be available at a later date.

Svein Mathisen, CEO of BioInvent, comments: “We conclude that BI-204 did not
meet the primary objective set out in the GLACIER study. Before deciding on the
future of BI-204, we and our partner Genentech need to finalize the full data
analysis. We expect to provide an update later this year.”

BioInvent will host a teleconference today at 11 am CET addressing the outcome
of the study. Participants are invited to dial in at: 08 505 20424 (Sweden) or
+44 (0)203 003 2666 (International), password BioInvent.

- END –

To the editors:

About GLACIER
GLACIER (Goal of oxidised Ldl and ACtivated macrophage Inhibition by Exposure to
a Recombinant antibody) enrolled 147 patients, exploring the anti-inflammatory
effect of BI-204, administered either as a single dose or in multiple doses,
compared to placebo on top of standard of care, including statins, in patients
with stable atherosclerotic cardiovascular disease. Vascular inflammation was
quantified by FDG-PET/CT imaging, with the primary endpoint defined as the
target-to-background ratio in the most diseased segment (MDS-TBR), a ratio
between the FDG uptake signal in the vessel wall and the background blood pool.

About BI-204
BI-204 (anti-oxLDL, MLDL1278A, RG7418) is a monoclonal antibody derived from
BioInvent’s proprietary n-CoDeR® technology. It is designed to target pro
-inflammatory macrophage activity in the atherosclerotic plaque by binding to
Oxidised LDL (Low-Density Lipoprotein). Vessel wall inflammation is regarded as
the underlying cause of the development of atherosclerosis and coronary artery
disease.

About BioInvent
BioInvent International AB, listed on the NASDAQ OMX Stockholm (BINV), is a
research-based pharmaceutical company that focuses on developing antibody drugs.
The Company currently has clinical development projects within the areas of
cancer and atherosclerosis. The Company has signed various strategic alliances
to strengthen the product pipeline and increase the likelihood of success. These
partners include Genentech, Human Genome Sciences and ThromboGenics.

The company’s competitive position is underpinned by n-CoDeR®, a proprietary
antibody development platform. The scope and strength of this platform is also
utilised by partners, such as Bayer HealthCare, Daiichi Sankyo, Mitsubishi
Tanabe and Servier. More information is available at www.bioinvent.com.

For further information, please contact:

BioInvent International AB
Svein Mathisen                                                      Sten
Westerberg
President & CEO                                                   Vice
President, Investor Relations
Phone:+46 (0)46 286 85 67                                Phone: +46 (0)46 286 85
52
Mobile: +46 (0)708 97 82 13                               Mobile: +46 (0)768 68
50 09
E-mail: svein.mathisen@bioinvent.com           E-mail:
sten.westerberg@bioinvent.com

College Hill (media enquiries)
Melanie Toyne Sewell
Phone: +44 (0)20 7457 2020
Rebecca Skye Dietrich
Phone: +1 (857) 241 0795
E-mail: bioinvent@collegehill.com

The Trout Group
Christine Yang
Vice President
Phone: +1 646 378 2929
E-mail: cyang@troutgroup.com

BioInvent International AB (publ)
Co. reg. No. 556537-7263,
Visiting address: Sölvegatan 41
Mailing address: SE-223 70 LUND
Phone: +46 (0)46 286 85 50
info@bioinvent.com
www.bioinvent.com

Legal disclaimer
The press release contains statements about the future, consisting of subjective
assumptions and forecasts for future scenarios. Predictions for the future only
apply as the date they are made and are, by their very nature, in the same was
as research and development work in the biotech segment, associated with risk
and uncertainty. With this in mind, the actual outcome may deviate significantly
from the scenarios described in this press release.

Information disclosed in this press release is provided herein pursuant to the
Swedish Securities Markets Act and/or the Swedish Financial Instruments Trading
Act. The information was submitted for publication at 8.00 a.m. CET, on 11 July,
2012.