The WATS3D Esophageal Biopsy Will Be Featured in Multiple Scientific Presentations at Digestive Disease Week

SUFFERN, NY--(Marketwired - May 11, 2015) - CDx Diagnostics today announced that three studies examining the WATS^3D biopsy will be presented at Digestive Disease Week 2015 (DDW), taking place from May 16-19, 2015 in Washington D.C. Among the highlights is an oral presentation evaluating the utility of WATS^3D in the detection of recurrent or residual disease following endoscopic ablation therapy.

The WATS3D biopsy addresses the sampling error inherent in small random esophageal forceps biopsies by collecting a wide area, disaggregated tissue specimen of the entire thickness of the suspect epithelium. This unique tissue specimen is then subjected to specialized, computer-assisted 3-dimensional analysis to pinpoint potentially abnormal cells for presentation to a pathologist. In clinical trials, adjunctive use of WATS^3D significantly increased the detection rate of both Barrett's esophagus and esophageal dysplasia in both screening^1-2 and surveillance³ populations. DDW attendees can visit booth # 1353 to learn more about WATS^3D.

"As a low-cost and rapidly implementable adjunct to routine upper endoscopy, WATS^3D can have a profound impact on patient care," said Mark Rutenberg, Chairman and CEO of CDx Diagnostics. "We are pleased to see the evidence base supporting WATS^3D continue to grow, and we believe these new data at DDW will reinforce its critical role in the care pathway for Barrett's esophagus."

A schedule of WATS^3D clinical studies and scientific presentations at DDW 2015 follows:

Oral Presentation

Sunday, May 17^th, from 10:00 AM - 11:30 AM, Room 144

Oral Presentation 345: "Transepithelial Brush Biopsy With Computer-Assisted Tissue Analysis Increases Detection Of Residual Or Recurrent Intestinal Metaplasia And Dysplasia Following Endoscopic Ablation Of Barrett's Esophagus"
Natalya Iorio, Brandon Sprung, Vivek Kaul, Danielle Marino, Shivangi Kothari, Truptesh H. Kothari, Rahul D. Kataria, Seth A. Gross, Michael S. Smith

Poster Presentations

Saturday, May 16^th, from 9:30 AM - 4:00 PM, HALL C

Poster Sa1891: "Increased Detection of Barrett's esophagus-associated Neoplasia using Wide-Area Trans-epithelial Sampling in Conjunction with 4-Quadrant Biopsies: Interim Results from a Multi-center, Prospective, Randomized Trial"
Prashanth Vennalaganti, Glenn Eisen, Gary W. Falk, Lauren B. Gerson, Seth A. Gross, John R. Goldblum, Neil Gupta, Gregory B. Haber, Anthony Infantolino, Prasad G. Iyer, David A. Johnson, Vivek Kaul, Shivangi Kothari, Charles J. Lightdale, Nicholas J. Shaheen, Michael S. Smith, Felice Schnoll-Sussman, Kenneth K. Wang, Yaxia Zhang, Prateek Sharma

Tuesday, May 19^th, from 9:30 AM - 4:00 PM, HALL C

Poster Tu1556: "Role of Spray Cryotherapy and WATS in Dysplastic Barrett's Esophagus Refractory to Radiofrequency Ablation"
Brandon Sprung, Christine M. Granato, Shivangi Kothari, Truptesh H. Kothari, Vivek Kaul

About CDx Diagnostics and the WATS^3D Biopsy
CDx Diagnostics' mission is to provide doctors with the most powerful diagnostic technology to help prevent cancer before it can start.

CDx Diagnostics' WATS^3D biopsy addresses the sampling error inherent in random forceps biopsy testing of the esophagus. In just a few minutes, gastroenterologists can easily obtain a wide area, full-thickness transepithelial tissue sample for computer-assisted 3D laboratory analysis. In clinical trials, adjunctive use of CDx Diagnostics' WATS^3D biopsy significantly increased the detection rate of both Barrett's esophagus and esophageal dysplasia. The high sensitivity of WATS^3D is due to the large tissue area sampled, and the proprietary 3-Dimensionial computer imaging system that is based on an algorithm developed as part of the U.S. Strategic Defense Initiative missile defense program. To learn more about WATS^3D, visit www.WATS3D.com.

About Digestive Disease Week®
Digestive Disease Week® (DDW) is the largest international gathering of physicians, researchers and academics in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery. Jointly sponsored by the American Association for the Study of Liver Diseases (AASLD), the American Gastroenterological Association (AGA) Institute, the American Society for Gastrointestinal Endoscopy (ASGE) and the Society for Surgery of the Alimentary Tract (SSAT), DDW takes place May 16-19, 2015, at the Walter E. Washington Convention Center, Washington, DC. The meeting showcases more than 5,000 abstracts and hundreds of lectures on the latest advances in GI research, medicine and technology. More information can be found at www.ddw.org.

References
1. Johanson JF, Frakes J, Eisen D et al. Computer-assisted analysis of abrasive transepithelial brush biopsies increases the effectiveness of esophageal screening: a multicenter prospective clinical trial by the EndoCDx Collaborative Group. Dig Dis Sci 2011;56:767-72.
2. Gross et al. Esophageal Brush Biopsy With Computer-Assisted Tissue Analysis Increases Detection of Barrett's Esophagus and Dysplasia in a Multi-Site Community-Based Setting. Presented at Digestive Disease Week; May 2-6, 2014. Chicago. Abstract 371.
3. Anandasabapathy S, Sontag S, Graham DY et al. Computer-assisted brush-biopsy analysis for the detection of dysplasia in a high-risk Barrett's esophagus surveillance population. Dig Dis Sci 2011;56:761-6.