Notice of AGM

NOTICE OF ANNUAL GENERAL MEETING

AstraZeneca PLC (the Company) announced today the publication of its Notice of
Annual General Meeting 2016 and Shareholders' Circular, together with a covering
letter from the Chairman.

Copies of the documents have been submitted to the National Storage Mechanism
and will shortly be available for inspection at www.morningstar.co.uk/uk/nsm.
The documents are also available on the Company's website at
www.astrazeneca.com/agm.

The Company's Annual Report and Form 20-F Information 2015 and AstraZeneca 2015
In Brief were published on 8 March 2016.

The above documents are being despatched to shareholders today.

The meeting place for the Annual General Meeting (AGM) will be the Lancaster
London Hotel, Lancaster Terrace, London, W2 2TY and the AGM will commence at
2.30 pm (BST) on 29 April 2016.

Since the effective date of the Company's Annual Report and Form 20-F
Information 2015, it has been announced that Leif Johansson, Non-Executive
Chairman of AstraZeneca PLC, has declined re-election to the board of Svenska
Cellulosa Aktiebolaget SCA (publ) at SCA's annual general meeting, which will be
held on 14 April 2016.

A C N Kemp
Company Secretary
18 March 2016