AstraZeneca completes agreement with LEO Pharma


This announcement contains inside information

16 August 2016 07:00

ASTRAZENECA COMPLETES GLOBAL LICENCING
AGREEMENT WITH LEO PHARMA FOR TRALOKINUMAB

AstraZeneca today announced that it has completed the licensing
agreement (https://www.astrazeneca.com/media-centre/press
-releases/2016/astrazeneca-enters-licensing-agreements-with-leo-pharma-in-skin
-diseases-01072016.html) with LEO Pharma A/S (LEO Pharma), a specialist in
dermatology care, for the global licence to tralokinumab in skin diseases.
Tralokinumab is an IL-13 monoclonal antibody that has completed a Phase IIb
trial for the treatment of patients with atopic dermatitis, an inflammatory skin
disease resulting in itchy, red, swollen and cracked skin.

Upon completion of the agreement, LEO Pharma made a payment to AstraZeneca of
$115 million for the exclusive, global rights to tralokinumab in atopic
dermatitis and any future additional dermatology indications. As AstraZeneca
will retain a significant ongoing interest in tralokinumab, the upfront payment,
along with all future commercial milestone and royalty payments, will be
reported as Externalisation Revenue in the Company's financial statements.

About AstraZeneca
AstraZeneca is a global, science-led biopharmaceutical company that focuses on
the discovery, development and commercialisation of prescription medicines,
primarily for the treatment of diseases in three therapy areas - Respiratory and
Autoimmunity, Cardiovascular and Metabolic Diseases, and Oncology. The Company
is also active in inflammation, infection and neuroscience through numerous
collaborations. AstraZeneca operates in over 100 countries and its innovative
medicines are used by millions of patients worldwide. For more information
please visit: www.astrazeneca.com

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Adrian Kemp
Company Secretary
AstraZeneca PLC

-ENDS-

Attachments

08160430.pdf