New York, USA, May 16, 2023 (GLOBE NEWSWIRE) -- Chronic Hepatitis B Market to Observe Stunning Growth at a CAGR of 13.4% by 2032 | DelveInsight
The chronic hepatitis B market is expected to grow significantly owing to increased R&D for developing new molecules, advancement in vaccine technology, expected commercial success of upcoming therapies, along with a hike in the usage of approved therapies in the 7MM and China.
DelveInsight’s Chronic Hepatitis B Market Insights report includes a comprehensive understanding of current treatment practices, chronic hepatitis B emerging drugs, market share of individual therapies, and current and forecasted market size from 2019 to 2032, segmented into 7MM [the United States, the EU-4 (Italy, Spain, France, and Germany), the United Kingdom, and Japan], and China.
Key Takeaways from the Chronic Hepatitis B Market Report
- As per DelveInsight analysis, the chronic hepatitis B market size in the 7MM + China was approximately USD 2.4 billion in 2022.
- According to the assessment done by DelveInsight, the estimated total prevalent chronic hepatitis B cases in the 7MM + China were approximately 81.3 million in 2022.
- Leading chronic hepatitis B companies such as GlaxoSmithKline, Ionis Pharma, Beijing Continent Pharmaceutical, Ascletis Pharmaceuticals, Vir Biotechnology, Brii Biosciences, Janssen, Arrowhead Pharmaceuticals, and others are developing novel chronic hepatitis B drugs that can be available in the chronic hepatitis B market in the coming years.
- The promising chronic hepatitis B therapies in the pipeline include Bepirovirsen (GSK3228836), Bepirovirsen (GSK3228836) followed by GSK3528869A, ASC22 (envafolimab), VIR-2218, VIR-3434, BRII-179 (VBI-2601), JNJ-73763989 (JNJ-3989) and others.
Discover which therapies are expected to grab the major chronic hepatitis B market share @ Chronic Hepatitis B Market Report
Chronic Hepatitis B Overview
Hepatitis B is a potentially fatal and one of the most prevalent liver illnesses caused by the hepatitis B virus (HBV), which targets and injures the liver. A hepatitis B infection can be acute or persistent. Hepatitis B is a “silent epidemic” since most people do not show symptoms when they are freshly infected or chronically sick. As a result, they risk unwittingly infecting others and extending the sluggish spread of hepatitis B. Hepatitis B symptoms include fatigue, low appetite, stomach pain, fever, nausea, vomiting, and, on rare occasions, joint pain, hives, or rash. The color of the urine may darken, and jaundice may appear. Although adults are more likely than children to develop symptoms, up to 50% of adults with acute infection have no symptoms.
As clinical findings cannot distinguish hepatitis B from other viral hepatitis, laboratory confirmation of the diagnosis is critical. Several blood tests are available to diagnose and monitor patients with CHB, including anti-HBc IgG, HBeAg, HBsAg quantitative, ALT, AST, AFP, and others. In severe situations, a liver biopsy may be required.
Chronic Hepatitis B Epidemiology Segmentation
DelveInsight estimates that there were approximately 81.3 million prevalent cases of chronic hepatitis B in the 7MM + China in 2022.
China contributed to the largest prevalent population of chronic hepatitis B, acquiring ~93% of the 7MM and China in 2022. Whereas the United States, EU4, the UK, and Japan accounted for around 2.8%,2.1%, 0.6%, and 1.5% of the total population share, respectively, in 2022.
The chronic hepatitis B market report proffers epidemiological analysis for the study period 2019–2032 in the 7MM + China segmented into:
- Chronic Hepatitis B Prevalent Cases
- Chronic Hepatitis B Diagnosed Prevalent Cases
- Chronic Hepatitis B Gender-specific Diagnosed Prevalent Cases
- Chronic Hepatitis B Age-specific Diagnosed Prevalent Cases
- Chronic Hepatitis B Impact on liver-specific Diagnosed Prevalent Cases
- Total Chronic Hepatitis B Treated Cases
Download the report to understand which factors are driving chronic hepatitis B epidemiology trends @ Chronic Hepatitis B Epidemiological Insights
Chronic Hepatitis B Treatment Market
The goals of chronic hepatitis B virus infection treatment are to minimize liver inflammation and to prevent consequences by reducing viral replication. Cirrhosis treatment can decrease the progression of the disease, lower the incidence of liver cancer, and enhance long-term survival. Patients with chronic hepatitis B are treated with antiviral medications, interferon injections, and liver transplants. Cirrhosis treatment can decrease the progression of the disease, lower the incidence of liver cancer, and enhance long-term survival.
Entecavir, tenofovir disoproxil fumarate, and tenofovir alafenamide (TAF) are the first-choice antiviral medicines. Interferon injections are mostly used for young persons with hepatitis B who want to forgo long-term treatment or for women who want to become pregnant within a few years after finishing a limited course of medication. In the case of chronic liver failure, liver transplantation may be considered. During a liver transplant, the surgeon will replace the diseased liver with a healthy one.
Due to the public health concern posed by chronic hepatitis B, the WHO announced in 2016 that it would be eradicated by 2030. With the advancement of antiviral medicines over the last decade, the treatment aim for chronic hepatitis B has shifted beyond viral suppression (i.e., prolonged undetectable HBV DNA levels) and seroconversion/loss of hepatitis B e antigen (HBeAg). Over the next few years, the US chronic hepatitis B market is expected to significantly change and grow, as interferon followed by TDF will dominate. In addition, we anticipate the debut of a new product in the US chronic hepatitis B market. VEMLIDY is predicted to take share mostly from its predecessor VIREAD and to reach a peak in the US by 2025, before generics.
To know more about chronic hepatitis B treatment guidelines, visit @ Chronic Hepatitis B Management
Chronic Hepatitis B Pipeline Therapies and Key Companies
- Bepirovirsen (GSK3228836): GlaxoSmithKline/Ionis Pharma
- Bepirovirsen (GSK3228836) followed by GSK3528869A: GlaxoSmithKline
- ASC22 (envafolimab): Ascletis Pharmaceuticals
- VIR-2218 and VIR-3434: Vir Biotechnology
- BRII-179 (VBI-2601): Brii Biosciences and Vir Biotechnology
- JNJ-73763989 (JNJ-3989) and JNJ-56136379 (JNJ-6379): Janssen and Arrowhead Pharmaceuticals
Learn more about the FDA-approved drugs for chronic hepatitis B @ Drugs for Chronic Hepatitis B Treatment
Chronic Hepatitis B Market Dynamics
The dynamics of the chronic hepatitis B market are anticipated to change in the coming years. One of the significant potentials driving the chronic hepatitis B market is the development of new diagnostic tools or methods for the early detection of chronic hepatitis B in the affected patient population. Moreover, chronic hepatitis B treatment in the United States is entering a new age marked by shifting dynamics. To date, the US FDA has approved numerous medications to treat chronic hepatitis B, including interferon-alpha and pegylated interferon-alpha, nucleoside analogs, and nucleotide analog prodrugs. VIREAD (tenofovir disoproxil), VEMLIDY (tenofovir alafenamide), BARACLUDE (entecavir), TYZEKA or SEBIVO (telbivudine), HEPSERA (adefovir dipivoxil), and lamivudine (Epivir-HBV, Zeffix, or Heptodin) are examples of oral antiviral drugs. The aforementioned treatments aid in the battle against the virus and decrease its ability to damage the liver.
Furthermore, the anticipated launch of new therapies and improved integration of early patient screening, medication in secondary care and other clinical settings, research on optimum implementation methods, and increased awareness, may eventually facilitate the development of successful treatment alternatives.
However, there are a few roadblocks to the growth of chronic hepatitis B such as delay in diagnosis and treatment of these patients, entry of generics due to patent expiration, and rising healthcare costs because the current treatment is lifelong. These variables frequently create a barrier to the adoption of innovative therapies in the chronic hepatitis B market. In addition, one of the major hurdles to the advancement of the chronic hepatitis B treatment paradigm is a lack of knowledge. Individuals who lack HBV knowledge may be vulnerable to infection. Thus all these factors may cause a dip in the growth of the chronic hepatitis B market in the coming years.
| Report Metrics | Details |
| Study Period | 2019–2032 |
| Coverage | 7MM [the United States, the EU-4 (Italy, Spain, France, and Germany), the United Kingdom, and Japan], and China |
| Base Year | 2019 |
| Chronic Hepatitis B Market CAGR | 13.4% |
| Chronic Hepatitis B Market Size in 2022 | USD 2.4 Billion |
| Key Chronic Hepatitis B Companies | GlaxoSmithKline, Ionis Pharma, Beijing Continent Pharmaceutical, Ascletis Pharmaceuticals, Vir Biotechnology, Brii Biosciences, Janssen, Arrowhead Pharmaceuticals, and others |
| Key Pipeline Chronic Hepatitis B Therapies | Bepirovirsen (GSK3228836), Bepirovirsen (GSK3228836) followed by GSK3528869A, ASC22 (envafolimab), VIR-2218, VIR-3434, BRII-179 (VBI-2601), JNJ-73763989 (JNJ-3989), and others |
Scope of the Chronic Hepatitis B Market Report
- Therapeutic Assessment: Chronic Hepatitis B current marketed and emerging therapies
- Chronic Hepatitis B Market Dynamics: Attribute Analysis of Emerging Chronic Hepatitis B Drugs
- Competitive Intelligence Analysis: SWOT analysis and Market entry strategies
- Unmet Needs, KOL’s views, Analyst’s views, Chronic Hepatitis B Market Access and Reimbursement
Discover more about chronic hepatitis B drugs in development @ Chronic Hepatitis B Clinical Trials
Table of Contents
| 1. | Chronic Hepatitis B Market Key Insights |
| 2. | Chronic Hepatitis B Market Report Introduction |
| 3. | Chronic Hepatitis B Market Overview at a Glance |
| 4. | Chronic Hepatitis B Market Executive Summary |
| 5. | Disease Background and Overview |
| 6. | Chronic Hepatitis B Treatment and Management |
| 7. | Chronic Hepatitis B Epidemiology and Patient Population |
| 8. | Patient Journey |
| 9. | Chronic Hepatitis B Marketed Drugs |
| 10. | Chronic Hepatitis B Emerging Drugs |
| 11. | 7MM and China Chronic Hepatitis B Market Analysis |
| 12. | Chronic Hepatitis B Market Outlook |
| 13. | Potential of Current and Emerging Therapies |
| 14. | KOL Views |
| 15. | Chronic Hepatitis B Market Drivers |
| 16. | Chronic Hepatitis B Market Barriers |
| 17. | Unmet Needs |
| 18. | SWOT Analysis |
| 19. | Appendix |
| 20. | DelveInsight Capabilities |
| 21. | Disclaimer |
| 22. | About DelveInsight |
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