Dublin, Jan. 30, 2025 (GLOBE NEWSWIRE) -- The "Oligonucleotide CDMO Market by Service (Contract Manufacturing (Clinical, Commercial), Development), Type (ASO, SiRNA, (CPG Oligos, gRNA)), Application (Therapeutic, Research, Diagnostic), End User (Pharma, Biotech) - Global Forecast to 2029" report has been added to ResearchAndMarkets.com's offering.
The global oligonucleotide CDMO market is projected to reach USD 6.73 billion in 2029 from USD 2.51 billion in 2024, with a CAGR of 21.8% during the forecast period.
Key factors driving market growth include increasing focus on the launch of novel oligo-based drugs and growing outsourcing to CDMOs. Oligonucleotides, such as antisense oligonucleotides (ASOs), small interfering RNAs (siRNAs), and aptamers, are being focused on due to the specificity and targeted action offered by these drugs. This has led to an increase in development activity followed by FDA approvals. For instance, in April 2023, Qalsody (tofersen) was approved by the US FDA for treating amyotrophic lateral sclerosis (ALS) associated with a mutation in the superoxide dismutase 1 (SOD1) gene. Additionally, expertise and lower costs incurred while outsourcing clinical development and manufacturing (clinical and commercial) further support the growth of this market.
The contract manufacturing segment accounted for the largest share in the oligonucleotide CDMO market, by service type, in 2023
In 2023, contract manufacturing segment accounted for the largest share of the oligonucleotide CDMO market. Factors such as expertise offered by CDMOs leading to the reduction in production timelines and improving production scalability, supported by an increase in the demand for oligonucleotide therapeutics are supporting the growth of this segment. Additionally, regulatory expertise offered by CDMOs further reduces time-to-market and operational risks is another factor driving the outsourcing of manufacturing to CDMOs.
The pharmaceutical and biotechnology companies end-user segment registered the highest growth rate and largest market share in the oligonucleotide CDMO market, by end user, during the forecast period
Pharmaceutical and biotechnology companies are major end user segments of the oligonucleotide CDMO market. The increasing clinical and commercial demand for oligo-based therapies drives pharma and biotech companies to engage CDMOs for production. Oligonucleotide synthesis is complex and requires specialized expertise, high-end technologies, and regulatory compliance. CDMOs have established infrastructure and systems in place for offering to these companies. Thus, pharmaceutical and biotechnology companies largely rely on CDMOs, mainly for manufacturing, fill-finish, and other services.
Asia Pacific: The fastest growing region in the oligonucleotide CDMO market
Asia Pacific region, with countries like China, India, Japan, and South Korea are experiencing rapid growth in their biopharmaceutical industries, with increased focus on innovative therapies such as oligonucleotide-based drugs. Additionally, the Asia Pacific region offers significant cost advantages for CDMO services due to lower labor, production, and operational costs. This is attracting global players to outsource manufacturing activities from the Asia Pacific region.
List of Oligonucleotide CDMO Companies Profiled in the Report:
- Bachem (Switzerland)
- Thermo Fisher Scientific Inc. (US)
- Agilent Technologies, Inc. (US)
- Maravai Lifesciences (US)
- GenScript (US)
- Wuxi Apptec (China)
- Eurofins Scientific (Luxembourg)
- Lonza (Switzerland)
- Danaher Corporation (US)
- Syngene International Limited (US)
- EUROAPI (France)
- Ajinomoto Co., Inc. (Japan)
- ST Pharm (South Korea)
- Kaneka Corporation (Japan)
- Aurigene Pharmaceutical Services Ltd. (India)
- PolyPeptide Group (Switzerland)
- Biospring (Germany)
- Oligo factory (US)
- Corden Pharma (Switzerland)
- LGC Biosearch Technologies (UK)
- Bio-Synthesis Inc (US)
- Microsynth (Switzerland)
- Synoligo Biotechnologies, Inc. (US)
- Hongene Biotech Corporation (China)
- Sylentis, S.A. (Spain)
- Creative Biogene. (US)
The report provides insights on the following:
- Analysis of key drivers (Growing focus on development and commercialization of oligo-based therapeutics), restraints (Complexities associated with oligonucleotide manufacturing), opportunities (Increasing use of oligos for CRISPR/Cas 9 application), and challenges (Lack of sustainable and eco-friendly supply chain) influencing the growth of the oligonucleotide CDMO market.
- Innovation: Detailed insights on upcoming technologies, research & development activities, in the oligonucleotide CDMO market
- Market Development: Comprehensive information about lucrative markets - the report analyses the oligonucleotide CDMO market across varied regions.
- Market Diversification: Exhaustive information about new services, untapped geographies, recent developments, and investments in the oligonucleotide CDMO market
- Competitive Assessment: In-depth assessment of market shares, growth strategies, and service offerings of leading players in the oligonucleotide CDMO market like- Bachem, Thermo Fisher Scientific, Agilent Technologies, EUROAPI, ST Pharm, Wuxi Apptec, Maravai Lifesciences and Biospring among others
Key Attributes:
| Report Attribute | Details |
| No. of Pages | 255 |
| Forecast Period | 2024 - 2029 |
| Estimated Market Value (USD) in 2024 | $2.51 Billion |
| Forecasted Market Value (USD) by 2029 | $6.73 Billion |
| Compound Annual Growth Rate | 21.8% |
| Regions Covered | Global |
Key Topics Covered:
Premium Insights
- Oligonucleotide CDMO Market Overview
- North America: Oligonucleotide CDMO Market, by Service Type & Country (2023)
- Oligonucleotide CDMO Market, by Type, 2024 vs 2029
- Oligonucleotide CDMO Market, by Application, 2024 vs 2029
- Oligonucleotide CDMO Market Share, by End-user, 2023
- Oligonucleotide CDMO Market: Geographic Growth Opportunities
Market Dynamics
Drivers
- Growing Focus on Development and Commercialization of Oligo-based Therapeutics
- Advantages of Contract Development and Manufacturing
- Increasing Focus on Precision/Personalized Medicine
- Technological Advancements
Restraints
- Complexities Associated with Therapeutic Oligonucleotide Manufacturing
Opportunities
- Increasing Use of Oligos in Crispr-Cas9 Applications
Challenges
- Lack of Sustainable and Eco-Friendly Supply Chain
Oligonucleotide CDMO Market, by Service Type
- Contract Manufacturing
- Commercial Stage - Flexible, Scalable Production Facilities to Propel Market Growth
- Clinical Stage - Growing Demand for Oligonucleotide-based Therapeutics to Drive Market
- Contract Development - Growing Focus on Reducing Manufacturing Risks to Support Market Growth
Oligonucleotide CDMO Market, by Type
- Antisense Oligonucleotides
- Specific Development & Manufacturing Requirements Well-Supported by Cdmos to Drive Market Growth
- Small Interfering RNA
- Potential in Therapeutic Applications to Drive Market Growth
Oligonucleotide CDMO Market, by Application
- Therapeutic Applications
- Growing Demand for Oligonucleotide-based Therapeutics to Drive Market Growth
- Research Applications
- Use of Oligos in Sequencing for Advancing Drug Development to Support Growth
- Diagnostic Applications
- Growing Applications in Molecular Diagnostics and Ivd to Propel Market
Oligonucleotide CDMO Market, by End-user
- Pharmaceutical & Biotechnology Companies
- Increased Investments in Oligonucleotide Drug Pipelines to Support Market Growth
- Diagnostic Companies
- Growth of Personalized Diagnostics to Propel Market
Company Profiles
Key Players
- Bachem
- Thermo Fisher Scientific Inc.
- Agilent Technologies, Inc.
- Wuxi Apptec
- Maravai Lifesciences
- Lonza
- Eurofins Scientific
- Danaher
- Genscript
- Syngene International
- Euroapi
- Ajinomoto Co.
- St Pharm
- Kaneka
- Polypeptide Group
- Aurigene Pharmaceutical Services Ltd.
- Biospring
Other Players
- Oligo Factory
- Corden Pharma
- LGC Biosearch Technologies
- Bi0-Synthesis, Inc.
- Microsynth
- Synoligo Biotechnologies, Inc.
- Hongene Biotech Corporation
- Sylentis
- Creative Biogene
For more information about this report visit https://www.researchandmarkets.com/r/m83iay
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